Among patients who received echinocandins, the association between caspofungin MIC and all-cause mortality rates remained significant (adjusted hazards ratio [aHR] for MIC [greater than or equal to]0.5 mg/L = 2.59, 95% CI 1.08-6.19, p = 0.033) after adjustment for intensive care unit stay (aHR = 3.8, 95% CI 1.71-8.45, p = 0.001) and monocytopenia
(aHR = 4.02, 95% CI 1.89-8.55, p<0.001).
Cytopenia (bicytopenia, monocytopenia
or pancytopenia) may also accompany the diseases mentioned above.
Which one is a risk factor for chemotherapy-induced febrile neutropenia in childhood solid tumors: Early lymphopenia or monocytopenia
? Pediatr Hematol Oncol 2006; 23: 143-51.
* an unexplained high white blood cell count, pancytopenia, bicytopenia or monocytopenia
of unknown origin.
With respect to absolute numbers, no cases of neutropenia or monocytopenia
Leukocyte analysis revealed decreased neutrophils and basophils, increased eosinophils, mild lymphocytosis and marked monocytopenia
, both of them stable.
As reported (13), endotoxin administration produces a rapid and transient leukopenia, followed by a release of mature and immature neutrophils from the bone marrow at 3 h and a sustained T lymphopenia and monocytopenia
by 6 h.
is invariably demonstrable, and neutropenia is present in most cases.
Clinical pathology results revealed leukocytosis with slight monocytopenia
, and markedly elevated concentrations of liver and muscle enzymes (Table 1).
Patients with HCL are often pancytopenic, and monocytopenia
is a characteristic finding.
(9) Prednisone reduces activation and proliferation of lymphocytes, inhibits the production of certain cytokines, such as IL-1, IL-2, IL-6, IL-11 and TNF [alpha], causes lymphopenia and monocytopenia
, and inhibits the differentiation of monocytes into macrophages.
Leucopenia, neutropenia, lymphopenia, monocytopenia
and thrombocytopenia were noticed in 5 mg/kg Pb acetate treated animals.