Red wine anthocyanins are rapidly absorbed in humans and affect monocyte chemoattractant protein 1 levels and antioxidant capacity of plasma.
Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease.
Particularly, the monocyte chemoattractant protein
(MCP)-1, which belongs to the C-C chemokine superfamily, induces the infiltration, activation and cytokine secretion of inflammatory cells.
Polymorphism of the monocyte chemoattractant protein
(MCP-1) gene is associated with the plasma level of MCP-1 but not with carotid intima-media thickness.
Monocyte chemoattractant protein
inhibits the generation of tumor-reactive T cells.
Regulation of monocyte chemoattractant protein
1 by cytokines and oxygen free radicals in rat hepatic fat-storing cells.
Interleukin-8 (IL-8) and monocyte chemoattractant protein
(MCP-1) are among the small proteins, termed chemokines, produced by immune system cells in response to microbial infections, especially viral infections.
To clarify the immune responses mediated by ficolins in the placenta during preeclamptic pregnancy, we found that chemokines/cytokines involved in innate immunity, including monocyte chemoattractant proteins
1/2/3 (MCP1/2/3), monokine induced by gamma-interferon (MIG), macrophage inflammatory proteins 1[delta]/3[alpha] (MIP1[delta]/3[alpha]), tumor necrosis factor [alpha] (TNF[alpha]) and thymus expressed chemokine (TECK) were activated, whereas interferon/cytokines involved in adaptive immunity, including interferon [gamma] (IFN[gamma]), interleukin 13/4/5 (IL13/4/5), transforming growth factor [beta]1/[beta]3 (TGF[beta]1/[beta]3) and TNF[beta], were suppressed in preeclamptic placenta (n = 10 vs 10; Fig.
The market scenario will change following the launch of new disease modifying therapies such as ACEs inhibitor, antioxidant inflammation modulator, connective tissue growth factor (CTGF) Inhibitor, monocyte chemoattractant proteins
(MCP) inhibitor, selective glycation inhibitor, transforming growth factor beta regulator, selective Endothelin-A Receptor (ETAR) antagonist, urotensin II receptor antagonist, IL-12 inhibitors and STAT-4 activator, Nox4 inhibitor, G protein-coupled receptors (GPCRs) antagonist, and erythropoiesis stimulating agent.