monoclonal gammopathy of unknown significance

monoclonal gammopathy of unknown significance (MGUS),

a gammopathy diagnosed by electrophoresis of serum of asymptomatic old people who have no other evidence of plasma cell neoplasia; in 20% of cases it evolves into plasma cell malignancy.

mon·o·clo·nal gam·mop·a·thy of un·known sig·ni·fi·cance

(MGUS) (mon'ō-klōn'ăl gam-mop'ă-thē ŭn-nōn' sig-nif'i-kăns)
A gammopathy diagnosed by electrophoresis of serum of asymptomatic old people who have no other evidence of plasma cell neoplasia; in 20% of cases, it evolves into plasma cell malignancy.
Synonym(s): benign monoclonal gammopathy.
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References in periodicals archive ?
Those patients without recognizable organ involvement are considered to exhibit a monoclonal gammopathy of unknown significance (MGUS).
The major plasma cell dyscrasias are (1) multiple myeloma, (2) monoclonal gammopathy of unknown significance, (3) solitary plasmacytoma of bone, (4) extramedullary plasmacytoma, and (5) heavy-chain disorders.
In the absence of any other clinical or laboratory evidence of a hematological dyscrasia, a diagnosis of monoclonal gammopathy of unknown significance (MGUS) was made.

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