gammopathy

(redirected from monoclonal g)
Also found in: Dictionary, Thesaurus.

gammopathy

 [gam-mop´ah-the]
abnormal proliferation of the lymphoid cells producing immunoglobulins; the gammopathies include multiple myeloma, macroglobulinemia, and Hodgkin's disease. Called also gammaglobulinopathy.
monoclonal g's plasma cell dyscrasias.

gam·mop·a·thy

(gă-mop'ă-thē),
A primary disturbance in immunoglobulin synthesis.

gammopathy

An abnormal ↑ in immunoglobulin production; monoclonal gammopathies–MGs are usually malignant Examples Myeloma, Waldenström's disease, CLL, heavy-chain disease, but may also be benign, appearing in amyloidosis and MG of undetermined significance; polyclonal gammopathies are usually benign and appear in inflammatory conditions–eg, angioimmunoblastic lymphadenopathy, cirrhosis, leishmaniasis, rheumatoid arthritis, SLE, TB. Note: Polyclonal gammopathies may occur as epiphenomena in lymphomas, Hodgkin's disease, metastatic adenoCA. See Biclonal gammopathy, Monoclonal gammopathy of undetermined significance.

gam·mop·a·thy

(gă-mop'ă-thē)
A primary disturbance in immunoglobulin synthesis.

gammopathy

Any abnormality, in quality or quantity, of the IMMUNOGLOBULINS present in the blood. Benign monoclonal gammopathy is an abnormal production of a single clone of an immunoglobulin. Gammopathies are associated with MYELOMATOSIS.
Full browser ?