monoclonal


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monoclonal

 [mon″o-klo´nal]
derived from a single cell; pertaining to a single clone.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

mon·o·clo·nal

(mon'ō-klō'năl),
In immunochemistry, pertaining to a protein from a single clone of cells, all molecules of which are the same; for example, in the case of Bence Jones protein, the chains are all κ or λ.
Farlex Partner Medical Dictionary © Farlex 2012

monoclonal

(mŏn′ə-klō′nəl)
adj.
Derived as clones from a single cell or produced by clones of a single cell: a monoclonal tumor.
n.
A monoclonal product, such as a monoclonal antibody.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

monoclonal

adjective Referring to a single clone of cells.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

mon·o·clo·nal

(mon'ō-klōn'ăl)
immunochemistry Pertaining to a protein from a single clone of cells, all molecules of which are the same.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

monoclonal

Of a group of cells derived from a single cell, all having the same GENOTYPE. Of a single CLONE of cells.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Monoclonal

Identical cells or proteins; cells (clones) derived from a single, genetically-distinct cell, or proteins produced by these cells.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
IBI101, a recombinant fully human anti-OX40 (tumour necrosis factor receptor superfamily member 4) monoclonal antibody, was developed by the company and has independent intellectual property rights.
"Uveal effusion should be considered in patients taking anti-PD-1 and/or PD-L1 monoclonal antibody therapy," the authors write.
Table 2: Prevalence of Monoclonal Gammopathy of Undetermined Significance
The reason for this discrepancy is not obvious, but there have been some previous reports of glomerulonephritis with monoclonal IgG deposits without detection of monoclonal proteins in serum or LCDD without the deposition of light chains in the glomerulus [7, 8].
Major extracts from the Table of Content of Therapeutic Monoclonal Antibodies Market, 2016-2022 report:
Over the past decade, we have tried several new approaches to protein electrophoresis in the hope that we can better detect small abnormal monoclonal immunoglobulins.
Besides hypogammaglobulinemia (2) and the poly-reactive autoantibodies, (3) patients with CLL have been shown to have monoclonal proteins.
Frank Plummer, former head of NML expressed happiness at the news that Canadian-designed monoclonal antibodies had been used in fighting Ebola.
Liver function test results were within reference intervals, except for a serum IgG concentration of 3500 mg/dL (reference interval, 690-1660 mg/dL; to convert to grams per liter, multiply by 0.01) in the absence of a monoclonal protein.
Monoclonal IgA proteins that migrate in the [beta] fraction may be obscured by healthy [beta]-migrating proteins and may not electrophorese as a discrete band.
New Delhi, India, April 13, 2013 --(PR.com)-- A huge patient pool, increasing prevalence of health insurance, strong biosimilar manufacturing capabilities and a largely unpenetrated market are expected to be the catalysts in driving the market for monoclonal antibodies in India.