monoclonal


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monoclonal

 [mon″o-klo´nal]
derived from a single cell; pertaining to a single clone.

mon·o·clo·nal

(mon'ō-klō'năl),
In immunochemistry, pertaining to a protein from a single clone of cells, all molecules of which are the same; for example, in the case of Bence Jones protein, the chains are all κ or λ.

monoclonal

/mono·clo·nal/ (-klōn´al)
1. derived from a single cell.
2. pertaining to a single clone.

monoclonal

(mŏn′ə-klō′nəl)
adj.
Derived as clones from a single cell or produced by clones of a single cell: a monoclonal tumor.
n.
A monoclonal product, such as a monoclonal antibody.

monoclonal

[mon′əklō′nəl]
Etymology: Gk, monos + klon, twig
pertaining to or designating a group of identical cells or organisms derived from a single cell or organism. Compare polyclonal.

monoclonal

adjective Referring to a single clone of cells.

mon·o·clo·nal

(mon'ō-klōn'ăl)
immunochemistry Pertaining to a protein from a single clone of cells, all molecules of which are the same.

monoclonal

Of a group of cells derived from a single cell, all having the same GENOTYPE. Of a single CLONE of cells.

Monoclonal

Identical cells or proteins; cells (clones) derived from a single, genetically-distinct cell, or proteins produced by these cells.

monoclonal

derived from a single cell; pertaining to a single clone.

monoclonal antibodies
identical immunoglobulin molecules formed by a single clone of plasma cells; may occur naturally in plasma cell myelomas or in vitro by the fusion of an antibody producing B lymphocyte with a non-antibody-producing myeloma B cell. The fused heterokaryon has the properties of immortality and production of a monoclonal antibody. For the most part, monoclonal antibodies are made in mouse systems.
monoclonal gammopathy
see monoclonal gammopathy.
References in periodicals archive ?
Major extracts from the Table of Content of Therapeutic Monoclonal Antibodies Market, 2016-2022 report:
Herold's team ultimately treated 42 people, half of whom received monoclonal antibodies.
The three antibodies that we picked are human monoclonal antibodies, targeting conserved epitopes of the envelope of HIV.
Our US partner is providing us with a monoclonal antibody for a first phase proof of principle project.
Although the monoclonal antibody has witnessed rapid development, and the market scale is expected to share 8%-10% of world's total in 2012, the market in China is still mainly occupied by imported products.
Yet the promise of monoclonal antibodies faded over the years.
Monoclonal Antibodies Phase 2 Clinical Trial Pipeline Insights
Flex Monoclonal Mouse AnO Human, CytokeraOn, Clone AE1 / AE3, Ready to use
Treatment early in the disease process with different monoclonal antibodies, as well as the immune-system-suppressing drug cyclosporin, can keep these mice diabetes-free.
The report provides an understanding and analysis of how and why companies enter cancer monoclonal antibody partnering deals.
The tumor cells came from an AIDS patient with Burkitths lymphoma, an especially deadly monoclonal cancer arising from a specific B-cell mutation.
In order to treat the life-threatening disease more efficiently and with enhanced specificity, monoclonal antibodies have become the most widely used cancer therapy.