Flow cytometric analysis of the blastic population was also consistent with a pure monoblastic
These patients often show balanced chromosomal translocations involving 11q23 (KMT2A/MLL) or 21q22 (RUNX1) and are associated with monoblastic
or myelomonocytic morphology (11,53,59,60).
eosinophils; 9872 AMLwith minimal differentiation; 9873 AML without maturation; 9874 AML with maturation; 9891 Acute monoblastic
and monocytic leukemia; 9895 AML with myelodysplasia-related changes (multilineage dysplasia); 9896 Acute myeloid leukemia, t(8;21)(q22; q22); 9897 Acute myeloid leukemia with t(9;1 1)(p22;q23);MLLT3-MLL; 9910 Acute megakaryoblastic leukemia; 9920 Therapy-related (acute) myeloid neoplasm (Khwaja et al.
(11-13) Histiocytic proliferations associated with acute monoblastic
leukemia are excluded from this diagnosis.
Among acute myeloid leukaemias, one case was categorised as acute myelomonocytic leukaemia and other was acute monoblastic
leukaemia based on morphology; 2 cases of AML needed further investigations for categorisation.
CD117 was aberrantly expressed in Acute Monoblastic
In literature, MS is classified according to the predominant cell type (blastic, monoblastic
, and myelomonocytic) .
transformation in chronic myelogenous leukemia: Presentation with massive hepatic involvement.
LC can be defined as myeloid sarcoma or granulocytic sarcoma, in which the infiltrate is characterized by neoplastic granulocytic precursors; otherwise, when the infiltrate is composed of neoplastic monocytic precursors (monoblasts and promonocytes), LC can be labeled monoblastic
Hematologic and molecular spontaneous remission following sepsis in acute monoblastic
leukemia with translocation (9;11): A case report and review of the literature.
Lubbert, "Hematologic and molecular spontaneous remission following sepsis in acute monoblastic
leukemia with translocation (9;11): a case report and review of the literature," European Journal of Haematology, vol.
leukemia: A clinical and biologic study of 74 cases.