monoamine oxidase

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Related to monoamine oxidase: Monoamine oxidase inhibitors, monoamine oxidase inhibitor diet


an amine containing only one amino group.
monoamine oxidase (MAO) a copper-containing enzyme that deaminates monoamines such as dopamine, epinephrine, norepinephrine, and serotonin. See also monoamine oxidase inhibitor.

a·mine ox·i·dase

1. an oxidoreductase containing copper, and perhaps pyridoxal phosphate, and carrying out the same reaction as amine oxidase (flavin-containing). Synonym(s): diamine oxidase, histaminase
2. an oxidoreductase containing flavin and oxidizing amines with the aid of O2 and water to aldehydes or ketones with the release of NH3 and H2O2. Acted upon by antidepressants. Synonym(s): adrenaline oxidase, monoamine oxidase, tyraminase, tyramine oxidase

monoamine oxidase

n. Abbr. MAO
An enzyme that catalyzes the oxidative breakdown of monoamines such as norepinephrine and serotonin, thus regulating synaptic transmission of monoamine neurotransmitters in the nervous system.

monoamine oxidase (MAO)

an enzyme that catalyzes the oxidation of amines. See also monoamine oxidase inhibitor.

monoamine oxidase

MAO, one of a group of enzymes found in brain cells, in peripheral adrenergic and dopaminergic nerve endings and in the intestinal wall and liver. These enzymes play an important part in the breakdown of the neurotransmitters NORADRENALINE, DOPAMINE and serotonin (5-hydroxytryptamine). Non-selective inhibition of these enzymes will elevate mood. Selective MAO-A enzymes act on serotonin; selective MAO-B inhibitor drugs act on phenylethylamine in the glial cells of the brain and elsewhere. The selective MAO-A inhibitor drugs are used to treat DEPRESSION and anxiety; selective MAO-B inhibitors are used to treat Parkinsonism.

monoamine oxidase,

n an enzyme that catalyzes the oxidation of amines.
monoamine oxidase inhibitor (MAOI),
n an agent that blocks the oxidation and deamination of monoamines. The action of the inhibitor may increase the presence of catecholamines, which have antidepressant properties, but it is used for a range of disorders. It can include isocarboxazid (Marplan), phenelzine (Nardil), and tranylcypromine (Parnate). There are relative contraindications of the use of the drug with local anesthetic agents delivered in the dental office.


an amine containing only one amino group.

monoamine oxidase
a cuproprotein enzyme that deaminates monoamines such as serotonin, epinephrine, norepinephrine, dopamine, tyramine and tryptamine. Called also MAO.
monoamine oxidase inhibitors
substances that inhibit the activity of monoamine oxidase, increasing catecholamine and serotonin levels in the brain; they are used as antidepressants and antihypertensives. Called also MAO inhibitors.
References in periodicals archive ?
Structures of glicoricone and licofuranone, and inhibitory effects of licorice constituents on monoamine oxidase.
Monoamine oxidase (MAO) is an enzyme that reduces neurotransmitters to their metabolites for excretion, thus providing an essential component of the normal cycle of transmitter production and excretion.
Avoid use of Karbinal ER with monoamine oxidase inhibitors (MAOIs) which prolong and intensify the anticholinergic (drying) effects of antihistamines.
An irreversible monoamine oxidase (MAO) inhibitor for treating the signs and symptoms of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa.
The once a day patch works by delivering selegiline, a monoamine oxidase inhibitor or MAOI, through the skin and into the bloodstream.
Among their topics are contributions to aggressive behavior from genes on the Y chromosome, quantitative trait locus analysis of aggressive behaviors in mice, the molecular architecture of pheromone sensing in mammals, serotenergic mechanisms in aggression, a typology of human aggression and its biological control, and the important of gene-environment interactions in the role of monoamine oxidase A in the etiology of antisocial behavior.
The decrease in DOPAC levels that occurs with the increase in extracellular DA after potassium perfusion is thought to reflect a decrease in intracellular DA metabolism by monoamine oxidase (Camarero et al.
Researchers at Birmingham University looked at 17 trials involving a group of drugs called monoamine oxidase type B inhibitors (MAOBIs), which are used to slow the progression of Parkinson's.
The drug is contraindicated in patients during the acute recovery phase of myocardial infarction or in patients with arrhythmias, heart block, conduction disturbances, congestive heart failure, allergies to cyclobenzaprine or other ingredients in Flexeril, hypothyroidism, or current or recent use (within 14 days after discontinuation) of monoamine oxidase inhibitors.
The SSRIs are boasting fewer side effects than the monoamine oxidase inhibitors and tricyclic anti-depressants.
MDMA also interacts dangerously with some prescription drugs (including monoamine oxidase inhibitors, a class of antidepressants), and it raises heart rate and blood pressure, of special concern for people with cardiovascular conditions.
Medications include antidepressants such as selective serotonin reuptake inhibitors (SSRIs) and monoamine oxidase inhibitors (MAOIs), as well as drugs known as high-potency benzodiazepenes.