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an amine containing only one amino group.
monoamine oxidase (MAO) a copper-containing enzyme that deaminates monoamines such as dopamine, epinephrine, norepinephrine, and serotonin. See also monoamine oxidase inhibitor.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
1. an oxidoreductase containing copper, and perhaps pyridoxal phosphate, and carrying out the same reaction as amine oxidase (flavin-containing). Synonym(s): diamine oxidase, histaminase
2. an oxidoreductase containing flavin and oxidizing amines with the aid of O2 and water to aldehydes or ketones with the release of NH3 and H2O2. Acted upon by antidepressants. Synonym(s): adrenaline oxidase, monoamine oxidase, tyraminase, tyramine oxidase
Farlex Partner Medical Dictionary © Farlex 2012
n. Abbr. MAO
An enzyme that catalyzes the oxidative breakdown of monoamines such as norepinephrine and serotonin, thus regulating synaptic transmission of monoamine neurotransmitters in the nervous system.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
monoamine oxidaseMAO, one of a group of enzymes found in brain cells, in peripheral adrenergic and dopaminergic nerve endings and in the intestinal wall and liver. These enzymes play an important part in the breakdown of the neurotransmitters NORADRENALINE, DOPAMINE and serotonin (5-hydroxytryptamine). Non-selective inhibition of these enzymes will elevate mood. Selective MAO-A enzymes act on serotonin; selective MAO-B inhibitor drugs act on phenylethylamine in the glial cells of the brain and elsewhere. The selective MAO-A inhibitor drugs are used to treat DEPRESSION and anxiety; selective MAO-B inhibitors are used to treat Parkinsonism.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005