monoamine


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Related to monoamine: monoamine hypothesis, monoamine oxidase inhibitor diet

monoamine

 [mon″o-am´ēn]
an amine containing only one amino group.
monoamine oxidase (MAO) a copper-containing enzyme that deaminates monoamines such as dopamine, epinephrine, norepinephrine, and serotonin. See also monoamine oxidase inhibitor.

mon·o·am·ine

(mon'ō-am'ēn, -in), Although this word is correctly stressed on the second-last syllable, U.S. usage often stresses it on the last syllable.
A molecule containing one amine group.
Synonym(s): monamine

monoamine

/mono·amine/ (mon″o-ah-mēn´) an amine containing one amino group, e.g., serotonin, dopamine, epinephrine, and norepinephrine.

monoamine

(mŏn′ō-ăm′ēn, -ə-mēn′)
n.
An amine compound containing one amino group, especially a compound that functions as a neurotransmitter.

monoamine

[mon′ō·am′in]
an amine containing one amine group.

monoamine

A class of molecules that contain one amino group connected to an aromatic ring by a two-carbon chain. The physiologically important monoamines derive from aromatic amino acids—phenylalanine, tyrosine, tryptophan—and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes. They include neurotransmitters and neuromodulators, in particular catecholamines (dopamine, epinephrine and norepinephrine) and tryptamines (serotonin and melatonin).

monoamine

Pharmacology A class of hormones or neurotransmitters–eg, catecholamines–dopamine, epinephrine, norepinephrine and indoleamines–serotonin, melatonin, which have 1 amine. See Catecholamine.

mon·o·am·ine

, monamine (mon'ō-ǎ-mēn', mon-amin)
A molecule containing one amine group.

monoamine

an amine containing only one amino group.

monoamine oxidase
a cuproprotein enzyme that deaminates monoamines such as serotonin, epinephrine, norepinephrine, dopamine, tyramine and tryptamine. Called also MAO.
monoamine oxidase inhibitors
substances that inhibit the activity of monoamine oxidase, increasing catecholamine and serotonin levels in the brain; they are used as antidepressants and antihypertensives. Called also MAO inhibitors.
References in periodicals archive ?
Structures of glicoricone and licofuranone, and inhibitory effects of licorice constituents on monoamine oxidase.
The two key neurotransmitters implicated in the monoamine hypothesis are noradrenaline and serotonin.
Catabolism of serotonin requires the activity of monoamine oxidase, and low levels of 5HIAA are predicted in this disorder (21).
Monoamine oxidase is an enzyme found in both neurons and liver cells.
Styrene inhibits monoamine oxidase A, but not monoamine oxidase B in monkey brain mitochondria.
For example, decreased libido has been reported in studies examining the sexual side effects of tricyclic and tetracyclic antidepressants, monoamine oxidase inhibitors, and SSRIs.
Selective Serotonin Reuptake Inhibitors, Reversible Inhibitors of Monoamine Oxidase-A, and Buspirone
The severity of the changes in the MAO A/B knockout mice compared to MAO A knockout mice supports the idea that the severity of autistic-like features may be correlated to the amounts of monoamine levels, particularly at early developmental stages," Shih said.
Student t-test was used to estimate the effect of VW on monoamine neurotransmitters and effects of diazepam on sleep and EEG delta activity.
They cover the subcellular trafficking of the aspartic protease BACE1: molecular mechanisms in the control of beta-amyloid generation; brain vesicular monoamine transporter and apoptosis: perspectives on development and neurodegeneration; the case for pre-symptomatic detection and treatment of Alzheimer's Disease; and semantically mediated integration of cognition in Homo sapien: evolution, grammar, uncertainty, and cognitive accuracy.
Tetrabenazine decreases the jerky, involuntary movements of chorea in Huntington's disease by reversibly inhibiting vesicular monoamine transporter 2, depleting monoamines presynaptically and depleting dopamine preferentially over norepinephrine and/or 5-hydroxytryptamine, according to its manufacturer, Prestwick Pharmaceuticals Inc.
The agency questioned the references used to support the efficacy claims, and also said that even though the brochure included information from the boxed warning, it did not include contraindications in uncontrolled narrow-angle glaucoma and with monoamine oxidase inhibitors.