monoacylglycerol


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mon·o·ac·yl·glyc·er·ol

(mon'ō-ās'il-glis'ĕr-ol),
Glycerol with an acyl moiety esterified to position 1 (that is, 1-monoacylglycerol) or position 2 (that is, 2-monoacylglycerol); an intermediate in the degradation and synthesis of lipids; 2-monoacylglycerols are a major end product of triacylglycerol degradation.
Synonym(s): monoglyceride
References in periodicals archive ?
The accumulation of these lipids was also accompanied by an elevation in triacylglycerol catabolites such as glycerol (p = 0.01 one-way ANOVA) and monoacylglycerols (MAGs).
They tended to accumulate neutral lipids, including monoacylglycerol, diacylglycerol, triacylglycerol, free fatty acids, and alkyl chain.
The degradation of 2-AG is also enzymatically degraded by FAAH (42) and more specifically, monoacylglycerol lipase.
Monoacylglycerol (MAG)-oleic acid has stronger antioxidant, anti-atherosclerotic, and protein glycation inhibitory activities than MAG-palmitic acid.
Lipases hydrolyze long chain triacylglycerol into diacylglycerol, monoacylglycerol, glycerol and fatty acids (Yamamoto and Fujiwara, 1995).
- US-based pharmaceutical company Abide Therapeutics has started enrollment and dosing in a Phase 1 PET occupancy study with ABX-1431, a first-in-class investigational monoacylglycerol lipase inhibitor, and [18F] ABX-1488, a human MGLL-specific PET ligand, the company said.
Lipases are a group of enzymes that catalyze the hydrolysis of triacylglycerols to diacylglycerol, monoacylglycerol, fattyacids and glycerols at the interface between aqueous and the lipid phase.
According to Morita [37], the occurrence of esterification reactions between acrylic acid and glycerol molecules can produce a mixture of monoacylglycerol, diacylglycerol, and triacylglycerol, depending on the number of hydroxyl groups of glycerol involved in the reaction, as illustrated in Eq.
Lipoprotein lipase is a "gatekeeper" for fatty acid uptake (Greenwood 1985), and HSL as the rate-limiting enzyme is thought to break down TAG functionally into diacylglycerol and then into monoacylglycerol (Holm et al.
* Enzymes that synthesize and degrade the endocannabinoids: These include fatty acid amide hydrolase or monoacylglycerol lipase.
Murthy Madiraju, Researcher at the CRCHUM, said when sugar is being used by the insulin secreting pancreatic beta-cell, it produces monoacylglycerol, a fat-like signal and this is associated with insulin release into blood; they found that the production of monoacylglycerol is essential for glucose-stimulated insulin secretion by the beta-cell.