CSF2A gene on chromosome 5q23-q31 that encodes colony stimulating factor 2 (granulocyte-macrophage), a cytokine that controls the production, differentiation and function of granulocytes and macrophages.
CSF2 is localised to a cluster of related genes at chromosome 5q31, a region associated with deletions in the 5q- syndrome and acute myelogenous leukaemia.
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molgramostinA granulocyte and MACROPHAGE colony stimulating factor used to treat white cell deficiency. It is prepared by recombinant DNA techniques (genetic engineering). A brand name is Leucomax.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005