The common diagnostic situations that call for immunohistochemical staining are the differential diagnoses of renal versus nonrenal neoplasms, histologic subtyping of renal cell carcinoma, diagnosis of possible metastatic renal carcinomas, and, less frequently, molecular prognostication
. With the refinement of molecular and histologic classification of renal neoplasms and the availability of more-effective molecular targeted therapy for specific renal neoplasms, immunohistochemical techniques are increasingly important in their diagnosis.
In addition, the book covers basic, translational, and health services research pertaining to neoplasia of the esophagus, with material on the biology of esophageal cancer, esophageal imaging and staging, histology, and molecular prognostication
. Recurrences, pain control, and palliative care are covered as well.