To better understand how the immune response causes these neurological changes, the researchers exposed pregnant mice to a synthetic molecular mimic
of a replicating virus.
Finally, a discussion of the differential diagnosis of tRCC, particularly Xp11 t-RCC, is not complete without acknowledging its molecular mimics
. Although these tumors may or may not primarily involve the kidney, they may be mistaken for primary or metastatic t-RCC in the absence of sufficient clinical information.
Glycomimetics--non-carbohydrate compounds that are molecular mimics
of carbohydrates--are increasingly in demand as therapeutic agents.
So far, he adds, investigators have had little luck finding smaller molecular mimics
of GDNF and artemin that could be taken as oral drugs.
Walensky said that molecular mimics
of these domains are showing great promise in early clinical trials, yet most of these drugs block three or more BCL-2 family proteins, rather than homing in on one specific cancer-causing target.
Rebek's approach is unique because his molecular mimics
are so small.