Bloom-Richardson grading

(redirected from modified Bloom-Richardson)

Bloom-Richardson grading

A histological system used to stratify breast cancer, in particular ductal carcinoma, into low, intermediate and high grades for the purposes of diagnosis and management.  It is based on three morphologic features:
• Degree of tubule duct formation;
• Mitotic activity;
• Nuclear pleomorphism of tumour cells (nuclear grade).

Bloom-Richardson combined scores
3-5—Well-differentiated (BR low grade)
6-7—Moderately differentiated (BR intermediate grade)
8-9—Poorly differentiated (BR high grade)
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Sood N, NS Jitendra, Y Poonam, "Comparative Study of Cytomorphological Robinson's Grading for Breast Carcinoma with Modified Bloom-Richardson Histopathological Grading," Pathology Research International, vol.
In present study, Robinson's cytological grading was done on cytology and compared with modified Bloom-Richardson system on paraffin embedded sections.
All cases were graded cytologically and histologically using cytologic Robinson's grading system and modified Bloom-Richardson histologic grading system, respectively.
Grading of invasive lobular cancers by the modified Bloom-Richardson score, which includes tubule formation, requires special consideration as lobular cancers do not tend to form tubules and many invasive lobular cancers are graded as 2.

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