modification of DNA

modification of DNA

A process in which secondary chemical residues (e.g., methyl, hydroxymethyl, glucosyl groups) are added to deoxyribonucleotides by an organism to regulate the way in which its genes produce protein products.
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Chemical modification of DNA bases, 5-methylcytosine, plays a key role in epigenetic gene regulation (Breiling and Lyko, 2015).
The specific signature results from a chemical modification of DNA called methylation, which can control the expression of genes like a dimmer on a light switch.
When colon, lung, breast, stomach and endometrial cancer is present, a "striking" chemical modification of DNA occurs, said researchers from the National Human Genome Research Institute (NHGRI) in the US.
To achieve this, we propose a new framework to explain how the modification of DNA methylation and telomere length may be linked and decoupled by the direct and indirect effects of oxidative stress at different stages during development.
Kinetin is believed to develop in cellular DNA as a product of the oxidative, secondary modification of DNA (Plant Sci.
Compared with living people, Neandertals and ancient Siberians known as Denisovans had slightly different patterns of DNA methylation --a chemical modification of DNA that doesn't change the information in genes but helps control gene activity.
The genome is programmed by the epigenome, which is composed of chromatin and a covalent modification of DNA by methylation.
DNA methylation - a type of chemical modification of DNA where a methyl group (CH3) can be added (hypermethylation) or removed (hypomethylation) - allows the researchers to look for genetic abnormalities within tumour samples.
Sodium bisulfite modification of DNA was performed using a protocol adapted from Gruanau et al.
Imprinting may be defined as a reversible modification of DNA that can lead to differential expression of maternally or paternally inherited genes.
Host specificity of DNA produced by Escherichia coli: bacterial mutations affecting the restriction and modification of DNA.
Bisulfite modification of DNA was conducted using the CpGenome DNA Modification Kit (Intergen).

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