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Nephrology The excretion of excessive (> 5 mg/dL) protein in the urine; normally, about 150 mg/day of protein is lost in the urine,13 is albumin,13 is Tamm-Horsfall glycoprotein; the rest is divided among actively secreted proteins–eg, retinol binding proteins, β2-microglobulin, Ig light chains and lysozyme; in absence of disease, large proteins are retained due to their size, while the smaller proteins are actively resorbed; proteinuria is most often caused by kidney disease, due to glomerular defects, and defective renal tubular resorption, and most often detected by screening with reagent strip–dipstick. See Functional proteinuria, Overflow proteinuria.
Proteinuria, severity
Severe ≥ 1.0 g/dL, due to glomerulonephritis, nephrotic syndrome, lupus nephritis, amyloidosis
Moderate ≥ 0.2 g/dL, ≤ 1.0 g/dL, due to CHF, drugs, acute infections, myeloma, chemical toxins
Mild 0.05-0.2 g/dL, due to polycystic kidneys, pyelonephritis, renal tubular defects
Proteinuria, patterns
Glomerular pattern Due to a loss of fixed negative charge on the glomerular capillary wall, allowing albumin and other large (≥ 68 kD) molecules to leak into Bowman's space–eg, in glomerulonephritis and nephrotic syndrome Lab ↓ albumin, antithrombin, transferrin, prealbumin, α1-acid glycoprotein, α1-antitrypsin
Hemodynamic pattern Due to rheostatic changes in the body, causing a loss of 20 to 68 kD molecules, seen in transient proteinuria, CHF, fever, seizures, excess exercise.
Overflow pattern Due to tissue/cell destruction that overwhelms renal capacity to excrete certain proteins–eg, Bence-Jones proteinuria and myoglobinuria
Tubular pattern Due to renal tubular dysfunction with loss of normally filtered low molecular weight (≤ 40 kD) molecules Lab ↓ β2-microglobulin and lysozyme–eg, Fanconi syndrome, Wilson's disease, interstitial nephritis, antibiotic-induced injury and heavy metal intoxication  


said of a disease or condition that interferes with normal activities, such as eating and ambulation, without completely blocking them out.

Patient discussion about moderate

Q. what does moderate drinking mean? I am addicted to drinks… oops! Not water but alcohol. My well-wishers advised and requested me to drink moderate. Is it so? If I have to hate my habit then I want to know what does moderate drinking mean.

A. To me, you know that you don't drink "moderately" if you are questioning it. And apparently those around you are noticing. The helpful thing is that you know it. Most people who drink will deny it. Maybe you should visit a local AA meeting and get a feel for what you are doing. There is plenty support there. It would be a good thing to nip it in the bud at this early point.

Q. Imedix site has helped me to learn about the symptoms of autism. Thanks for the moderator and the members. Imedix site has helped me to learn about the symptoms of autism. Thanks for the moderator and the members. Now kindly add to my knowledge by letting me know whether there are any indications that require IMMEDIATE evaluation for autism?

A. Thank you Zakary. Though there are many symptoms of autism, a child should definitely be evaluated for autism immediately, if he or she has: No babbling by 12 months, No gesturing (pointing, aving bye-bye, etc.) by 12 months, No single words by 16 months. No two-word (not just echolalic) phrases by 24 months, any loss of any language or social skills at any age.

Q. what are the requirements of getting medicinal marijuana? i'd like to know the requirements of getting prescribed medicinal marijuana. i have heard alot about health benefits of moderate use of marijuana or should i refer to it as cannabis.

A. marijuana has been proven to help in these diseases,but the problem is getting a drs order for it.IT is easyer to get it under the table than legally.

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References in periodicals archive ?
In many ways, L'Allegro, il Penseroso ed il Moderato is the grand choreographic centerpiece in the career of Morris, whose company is celebrating its 20th season this year.
Kantor's lead has also inspired application of the field approach to research in several areas of which the following are recent examples: language behavior (Bijou, Chao, & Ghezzi, 1988; Bijou, Umbreit, Ghezzi, & Chao, 1986; Chiasson & Hays, 1993), intellectual retardation (Ghezzi & Bijou, in press; Ghezzi, Bijou, Umbreit, & Chao, 1987; Schussler & Spradlin, 1991), setting factors (Brown, Bryson-Brochman, & Fox, 1986; Brown, Fox, & Brady, 1987; Fox, 1990; Ray, 1984; Wahler & Fox, 1981), cognitive behaviors (Caracciolo, Moderato, & Ferini, 1988, 1990), and, together with system analysis, educational field systems (Ray, 1992; Ray & Delprato, 1989; Sharpe & Hawkins, 1992a; 1992b).
NYSE: TEVA) announced today enrollment of the first patient in the MODERATO study - a Phase IV clinical study designed to evaluate the effect of AZILECT([R]) (rasagiline tablets) on cognitive function in adults with mild cognitive impairment (MCI) in Parkinson's disease (PD-MCI).
It is more useful to go through this chapter point by point and seek out particular movements in Mozart's opuses in which one has a practical interest and compare them with movements of the same tide in a given category, as for example Allegro moderato in secular music.
This Sonatina's first movement is in D minor, its tempo indication is allegro moderato, and is alla breve (cut time).
It was a masterful and taut reading, from the murmuring opening of the beautifully-controlled moderato to the final moments of the closing andante-allegro.
His shaping of the opening Moderato, full-bodied tonally yet with an air of soulful questing, was perfectly judged, and in the luminescent Adagio religioso reached a plateau of almost salving calm.
These qualities all shone through in one of his favorite roles, the Lark in Morris' sublime L'Allegro, il Penseroso ed il Moderato.
She began, with the gramophone, singing it moderato expressivo, just as the music said.
The second Moderato movement, Memories, was supremely well judged and moving, while Fischer and the orchestra lingered on the tragic aspects of the profound Adagio, convincing us that this symphony is more than a crude outpouring of nationalistic fervour.
By contrast, "Bruderlein und Schwesterlein" was slower than the Allegretto moderato Strauss marked.
The orchestra delivered the following movement, the "Andante moderato," with a sense of noble seriousness.