Mobile genetic element
, Transposons were extensively studied in genome of bacteria, plants, animals including human but in 1989 transposons based molecular analysis was reported from filamentous fungi (Kempken et al., 1998).
Identification of a Putative Mobile Genetic Element
. The genetic regions up- and downstream of the tirE locus in the E.faecium E1162 genome sequence were compared to the corresponding regions of the community strain E.
The fourth region (R4, 14 ORFs from ORF20 to ORF40) mainly contains a mobile genetic element
. It includes a fragment (named R4') inserted into the umuC gene, which is characterized by a phage integrase (ORF38) and a phage integrase family site-specific recombinase (ORF37) and encodes 9 genes from different origins with various functions.
His primary research interests include investigating the transmission and epidemiology of important resistance genes and mobile genetic element
using next-generation sequencing.
Nucleotide sequence of IS26, a new prokaryotic mobile genetic element
. Nucleic Acids Res 1983; 11: 6319-6330.
Resistance to antibiotic can be conferred by chromosomal or mobile genetic element
(plasmids) (Jain et al., 2009) .
aureus organisms acquire a large mobile genetic element
called staphylococcal cassette chromosome mec (SCCmec) (6).
This finding suggests that armA could be part of a mobile genetic element
that has translocated between plasmids of diverse evolutionary origins.
SCCmec is a mobile genetic element
that carries the mecA gene, which mediates methicillin resistance in staphylococci.
denomination ) with PVL in the CA-MRSA strains most likely did not result from co-acquisition of the two determinants on a single mobile genetic element
because the two loci are widely separated on the S.
These bacteria are an important reservoir of antimicrobial resistance genes and mobile genetic elements
that can be transferred between staphylococcal species.
Microbes in healthy individuals may acquire AMR genes through: association with mobile genetic elements
(MGE) that undergo horizontal gene transfer (HGT) from microbes in the environment, especially from overcrowded living conditions, poor sanitation and farming where antimicrobial drugs are constantly administered to animals; and misuse of antibiotics from a previous infection i.e.