A 2016 meta-analysis of 5 RCTs with a total of 553 patients examined the effectiveness of add-on treatment with spironolactone (25-50 mg/d) for patients with resistant hypertension, defined as failure to achieve BP < 140/90 mm Hg
despite treatment with 3 or more BP-lowering drugs, including one diuretic.
04 mm Hg
across the four baseline SBP categories (P= .004).
Overall, average 24-hour systolic blood pressure was 5.3 mm Hg
lower among those who napped compared with those who didn't (127.6 mm Hg
vs 132.9 mm Hg
"If a patient gets to less than 140 mm Hg
, the doctor should not think that's a failure; it's a very important result."
* Stage 1 hypertension: SBP 130-139 mm Hg
or DBP 80-89 mm Hg
The handgrip induced SBP changes observed in the male cases at 1 min (138.0 [+ or -] 0.8 mm Hg
), 3 min (138.0 [+ or -] 1.34 mm Hg
) and 5 min (137.0 [+ or -] 1.45 mm Hg
) were significantly different than female cases at 1 min (145.8 [+ or -] 2.84 mm Hg
), 3 min (147.6 [+ or -] 2.74 mm Hg
) and 5 min (144.0 [+ or -] 1.83 mm Hg
), respectively (P < 0.05 for two-way ANOVA; Figures 2 and 3, Table 1).
The practical question is whether it is realistic to expect patients to achieve a systolic blood pressure of 120 mm Hg
. Blood pressure is notoriously difficult to lower.
The mean preoperative IOP was 28.52 mm Hg
. Mean postoperative IOP 13.64 mm Hg
at 3 months of follow up.
"Patients could not be classified as having BP that was in or out of control with 80% certainty on the basis of a single clinic SBP measurement from 120 mm Hg
to 157 mm Hg
," the authors state.
A difference of 15 mm Hg
or more in systolic blood pressure between a patient's arms may signal the presence of asymptomatic peripheral vascular disease, according to a meta-analysis.
It defines normal blood pressure as a systolic blood pressure (SBP) <120 millimeters of Mercury (mm Hg
) and a diastolic blood pressure (DBP) <80 mm Hg
Hypertension is defined as systolic blood pressure greater than 140 mm Hg
and diastolic blood pressure greater than 90 mm Hg