Mitoxantrone resistance protein | definition of mitoxantrone resistance protein by Medical dictionary
ABCG2 (redirected from mitoxantrone resistance protein)
ABCG2 A gene on chromosome 4q22, which encodes a xenobiotic transporter protein of the ATP-binding cassette (ABC) superfamily, White subfamily. It plays a major role in multi-drug resistance to chemotherapeutics, and is highly expressed in the placenta, but its role there is unknown.
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References in periodicals archive
Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein
(ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.