mitotic index


Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia, Wikipedia.

mi·tot·ic in·dex

the ratio of cells in a tissue that are undergoing mitosis, often expressed as either the number of cells in a specified area of tissue section or as a percentage of the total cell sample.

mitotic index

The percentage of cells in a population that are actually undergoing MITOSIS. The mitotic index is a measure of the reproductive or growth activity of a tissue.
References in periodicals archive ?
Prognostic considerations for MCTs include grade, clinical stage, location, systemic symptoms, status of surgical margins, and mitotic index. Mast cell tumors that are completely removed and are Low-Grade, Grade I, or Grade II with a low mitotic index and free of metastasis have an excellent prognosis, with most cases being considered cured.
Similar to the second biopsy, the mitotic index was 16 per 10 x400 fields (2.37 [mm.sup.2]), and numbers of karyomegalic and multinucleated cells were increased compared to the initial mass.
Tumors displaying malignant behaviors are assessed by tumor size and the mitotic index per 50 high power feld (HPF).
The mitotic index (MI) were calculated as the number of dividing cells as a fraction of the total number of cells, and the frequency of chromosome (CA) and nuclear alterations (NA), expressed as the percentage of number of alterations divided by the total number of cells (Aragao et al., 2015).
Liver regeneration parameters Parameters Sham (n=10) Control (n=11) Thymidine kinase (U/L) 4.6[+ or -]1.0 (cd) 6.2[+ or -]3.3 (cd) Regeneration rate (%) - 2.9[+ or -]0.1 (ce) Mitotic index (%) 0.1[+ or -]0.1 (cd) 0.4[+ or -]0.8 (cd) Parameters EGb761 (n=11) FK506 (n=10) Thymidine kinase (U/L) 9.5[+ or -]4.08 (ab) 9.8[+ or -]2.9 (abe) Regeneration rate (%) 6.6[+ or -]1.3 (bde) 4.4[+ or -]1.7 (c) Mitotic index (%) 6.1[+ or -]5.4 (ab) 5.2[+ or -]4.0 (ab) Parameters EGb761 + FK506 (n=11) (p) Thymidine kinase (U/L) 5.4[+ or -]3.13 (d) <0.001* Regeneration rate (%) 4.6[+ or -]1.6 (bc) <0.001* Mitotic index (%) 3.4[+ or -]2.2 <0.001* Data are reported as the mean [+ or -] standard deviation.
Previous studies have suggested that tumor size is the only important independent prognostic factor in multivariate analysis for DFS after R0 resection of gastric GISTs [18], while others argue that the mitotic index was an independent factor in multivariate analysis [19,20].
Contrarily, the mitotic index (%MI) showed a general trend for a decrease with the increase of Cr(VI), with significant differences for the higher Cr(VI) concentrations.
11 of 13 cases had a mitotic index of [less than or equal to] 1 mitosis/50 HPF, and all cases had a mitotic count [less than or equal to] 4 mitoses/50 HPF.