mitogen

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Related to mitogenicity: mitogenesis

mitogen

 [mi´to-jen]
a substance that induces blast transformation; DNA, RNA, and protein synthesis; and proliferation of lymphocytes; e.g., concanavalin A, phytohemagglutinin, or lipopolysaccharide.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

mi·to·gen

(mī'tō-jen),
A substance frequently derived from plants that stimulates mitosis and lymphocyte transformation in an antigen-nonspecific manner; includes not only lectins such as phytohemagglutinins, pokeweed mitogen, and concanavalin A, but also substances from streptococci (associated with streptolysin S) and from strains of α-toxin-producing staphylococci.
Synonym(s): transforming agent (1)
[mitosis + G. -gen, producing]
Farlex Partner Medical Dictionary © Farlex 2012

mitogen

(mī′tə-jən)
n.
An agent that induces mitosis.

mi′to·gen′ic (mī′tə-jĕn′ĭk, mĭt′ə-) adj.
mi′to·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

mi·to·gen

(mī'tō-jen)
A substance that stimulates mitosis and lymphocyte transformation; includes not only lectins such as phytohemagglutinins and concanavalin A, but also substances from streptococci (associated with streptolysin S) and from strains of α-toxin-producing staphylococci.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

mitogen

1. Any agent that promotes cell nuclear division (MITOSIS). Mitogens are important in genetic research and technology. Pokeweed mitogen, derived from the plant Phytolacca americana , is a powerful mitogen of B LYMPHOCYTES.
2. Any substance that non-specifically causes lymphocytes to proliferate.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

mitogen

a growth factor in the form of a small protein found in blood serum that often has a specific target organ in which it induces MITOSIS.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

mi·to·gen

(mī'tō-jen)
A substance that stimulates mitosis and lymphocyte transformation; includes not only lectins such as phytohemagglutinins and concanavalin A, but also substances from streptococci and from strains of α-toxin-producing staphylococci.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
TNF-[alpha] Stimulates Both Viability and Mitogenicity of C2C12 Myoblasts in NF-[kappa]B- and JAK/STAT-Dependent Manner.
Moreover, mitogenicity has nothing to do with muscle fiber decay and resulting muscle cachexia.
The most important of these criteria, mitogenicity, has been incorporated into the new AJCC staging model.
Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity. Blood.
The Melanoma Task Force of the AJCC has reviewed our studies and those of other authors and has developed an extensive database to externally validate mitogenicity as a prognostic factor.
Mitogenicity and release of vascular endothelial growth factor with and without heparin from fibrin glue.
Comparison of the pyrogenicity, Limulus activity, mitogenicity and complement reactivity of several bacterial endotoxins and related compounds.