mitogen

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Related to mitogenicity: mitogenesis

mitogen

 [mi´to-jen]
a substance that induces blast transformation; DNA, RNA, and protein synthesis; and proliferation of lymphocytes; e.g., concanavalin A, phytohemagglutinin, or lipopolysaccharide.

mi·to·gen

(mī'tō-jen),
A substance frequently derived from plants that stimulates mitosis and lymphocyte transformation in an antigen-nonspecific manner; includes not only lectins such as phytohemagglutinins, pokeweed mitogen, and concanavalin A, but also substances from streptococci (associated with streptolysin S) and from strains of α-toxin-producing staphylococci.
Synonym(s): transforming agent (1)
[mitosis + G. -gen, producing]

mitogen

(mī′tə-jən)
n.
An agent that induces mitosis.

mi′to·gen′ic (mī′tə-jĕn′ĭk, mĭt′ə-) adj.
mi′to·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.

mi·to·gen

(mī'tō-jen)
A substance that stimulates mitosis and lymphocyte transformation; includes not only lectins such as phytohemagglutinins and concanavalin A, but also substances from streptococci (associated with streptolysin S) and from strains of α-toxin-producing staphylococci.

mitogen

1. Any agent that promotes cell nuclear division (MITOSIS). Mitogens are important in genetic research and technology. Pokeweed mitogen, derived from the plant Phytolacca americana , is a powerful mitogen of B LYMPHOCYTES.
2. Any substance that non-specifically causes lymphocytes to proliferate.

mitogen

a growth factor in the form of a small protein found in blood serum that often has a specific target organ in which it induces MITOSIS.

mi·to·gen

(mī'tō-jen)
A substance that stimulates mitosis and lymphocyte transformation; includes not only lectins such as phytohemagglutinins and concanavalin A, but also substances from streptococci and from strains of α-toxin-producing staphylococci.
References in periodicals archive ?
TNF-[alpha] Stimulates Both Viability and Mitogenicity of C2C12 Myoblasts in NF-[kappa]B- and JAK/STAT-Dependent Manner.
Moreover, mitogenicity has nothing to do with muscle fiber decay and resulting muscle cachexia.
The most important of these criteria, mitogenicity, has been incorporated into the new AJCC staging model.
Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity. Blood.
The Melanoma Task Force of the AJCC has reviewed our studies and those of other authors and has developed an extensive database to externally validate mitogenicity as a prognostic factor.
Mitogenicity and release of vascular endothelial growth factor with and without heparin from fibrin glue.
Comparison of the pyrogenicity, Limulus activity, mitogenicity and complement reactivity of several bacterial endotoxins and related compounds.