PDGF induce tyrosine phosphorylation in osteoblast like cells"relevance to mitogenesis
Am J Physiol 1992; 263: 205-209.
Moreover it has been shown that TGF-[beta]1 combined with PDGF-BB and IGF-1 stimulated mitogenesis
and enhanced the adhesion of human PDL cells to human periodontally diseased root fragments treated by scaling and root conditioning with a citric acid and tetracycline solution .
Calcium crystals added into cell culture induced cell mitogenesis
and the production of matrix metalloproteinases (MMPs), nitric oxide, and inflammatory cytokines including interleukin-1[beta] and cyclooxygenase-2 [9-13].
These molecules are involved in many cellular processes such as cell adhesion, cellular differentiation, motility, and mitogenesis
Grattan, "Prolactin-induced mitogenesis
in the subventricular zone of the maternal brain during early pregnancy is essential for normal postpartum behavioral responses in the mother," Endocrinology, vol.
In particular, in contrast to mature B cells for which stimulation of the BCR is associated with mitogenesis
and increased proliferation, WEHI-231 in a process similar to immature B cells undergoes growth arrest and apoptosis in response to BCR stimulation [13,14].
Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis
. Cell Growth Differ.
Neuregulin-1 isoform induces mitogenesis
, KCa and Ca2+ currents in PC12 cells.
La enfermedad periodontal podria constituirse en un factor de riesgo para la disfuncion endotelial, dado que las citocinas proinflamatorias producidas por monocitos (IL-1, IL-6 y factor de necrosis tumoral [FNT]), como consecuencia de la infeccion periodontal, inhiben las lipasas lipoproteinas, por lo que la lipidemia es un factor prominente de las infecciones cronicas, a la vez que sobrerregula la expresion de la adhesion molecular sobre las celulas endoteliales y pueden estimular la mitogenesis
y la produccion de fibrinogeno.
Chao et al., "Role of MAP kinase activation in bovine tracheal smooth muscle mitogenesis
," American Journal of Physiology: Lung Cellular and Molecular Physiology, vol.
In 1980, Brahmi and Cooper reported that the native Androctonus australis hemolymph and its partial fraction 1 (eluted by chromatography in G-200 Sephadex column at a maximum of 280-340 nm, with 0.01 molarity and an elution pH of 8.05) stimulated the human, rabbit, and mouse lymphocytes mitogenesis
in in vitro studies.
Indeed, hormone-dependent, type I endometrial cancers are thought to arise due to excess estrogen stimulation, unopposed by progesterone, promoting mitogenesis
, atypical hyperplasia, and the transition to malignant adenocarcinoma [4, 8, 11].