Pae, "Mitogen-activated protein kinases
and reactive oxygen species: how can ROS activate MAPK pathways?" Journal of Signal Transduction, vol.
Differential activation of mitogen-activated protein kinases
in experimental mesangioproliferative glomerulonephritis.
Oestrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogen-activated protein kinase
in MCF-7 breast cancer cells.
Activation of mitogen-activated protein kinases
(Erk1 and Erk2) cascade results in phosphorylation of NF-M tail domains in transfected NIH 3T3 cells.
Davis, "Transcription factor AP-1 regulation by mitogen-activated protein kinase
signal transduction pathways," Journal of Molecular Medicine, vol.
Strniskova, "Mitogen-activated protein kinase
: a new therapeutic target in cardiac pathology," Molecular and Cellular Biochemistry, vol.
Yamaguchi, "Acidic pH stimulates the production of the angiogenic CXC chemokine, CXCL8 (interleukin-8), in human adult mesenchymal stem cells via the extracellular signal-regulated kinase, p38 mitogen-activated protein kinase
, and NF-[kappa]B pathways," Journal of Cellular Biochemistry, vol.
Research continues to elucidate new pathological mechanisms and develop new oral agents including Janus kinase (Jak), protein kinase C (PKC), and mitogen-activated protein kinase
(MAPK) inhibitors (Figure 2).
In which, KRAS, as one of the mitogen-activated protein kinase
(MAPK) signaling pathways, the RAS-RAF-MEK-ERK signaling pathway is a key pathway in many signaling pathways that control cell growth, proliferation, differentiation and apoptosis.
They discovered that the protein prohibitin occurs in high concentrations on the surface of certain T cells in MS patients and that its presence is associated with stimulation of the member of the mitogen-activated protein kinase
(MAPK) pathway called CRAF.
Glucocorticoid receptor (GR) and mitogen-activated protein kinase
phosphatase 1 (MKP-1) expression were detected by polymerase chain reaction and Western blotting (WB).
Extracellular signal-regulated kinase 5 (Erk5), which is a member of the mitogen-activated protein kinase
(MAPK) family, is phosphorylated by MAPK/Erk kinase-5 (Mek5) to regulate the function of various cell types.