IMMT

(redirected from mitofilin)

IMMT

A gene on chromosome 11p15.5 that encodes mitofilin (mitochondrial inner membrane protein), an ATP-driven motor protein primarily expressed in muscle, which interacts with cytoskeletal components.
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MA-5 targets the mitochondrial protein mitofilin at the crista junction of the inner membrane and can be a novel agent for treating diseases associated with mitochondrial dysfunction [5, 6].
Lewis et al., "Transgenic overexpression of mitofilin attenuates diabetes mellitus-associated cardiac and mitochondria dysfunction," Journal of Molecular and Cellular Cardiology, vol.
Sections were probed with anti-mouse mitofilin (MitoSciences, Eugene, OR), anti-rabbit Dnm1l (Origene), and anti-rabbit Calbindin1 (Swant, Marly, Switzerland).