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(mith'ri-dā'tizm, mith-rid'ă-tizm),
Immunity against the action of a poison produced by small and gradually increasing doses of the same.
[Mithridates, King of Pontus (132-63 BCE), supposedly an unsuccessful suicide (by poison) because of repeated small doses taken to become invulnerable to assassination by poison]
Farlex Partner Medical Dictionary © Farlex 2012


Tolerance or immunity to a poison acquired by taking gradually larger doses of it.

mith′ri·dat′ic (-dăt′ĭk) adj.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Tolerance against a toxin, induced by gradually increasing its levels in the body, a technique which is similar to tolerisation therapy in allergy medicine
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
To dramatize the complexity as well as the limitations of Terence's Mithridatic education, Housman creates a rhetorical regress of ironic distance among Terence the present-tense speaker of each poem, Terence the wiser but still imperfect author of the poems, and Housman himself, using what he has imbibed from Blake and Wordsworth.
As he announces in LXII, the Mithridatic effect of consuming poison is not only to accustom one to greater amounts of "ill," including the bitter draught of self-knowledge, but also to be, like Mithridates, a good, "seasoned sound" ruler of oneself and others.
There, in what became known as the First Mithridatic War, he eventually forced Mithridates to capitulate.
His accounts of the Iberian, African, and Mithridatic wars are noteworthy for the author's sympathy with subjugated peoples and his unstinting criticism of Roman brutality.
None the less, setting aside questions concerning its intelligibility and plausibility, the Mithridatic theory is still vulnerable to a variation of the argument from substitutability.
For all its obscurities, the inscription remains the best evidence of the intervention of a Roman commander in the internal affairs of a Greek city between the Achaean and Mithridatic Wars.
It has assumed its winter aspect,--a Mithridatic look.
Principal wars: Third Mithridatic War (75-65), Gallic War (59-51), war with Pompey (49-45).
This man was now set loose on the people by Marius and after shaking everything up by force he proposed a number of vicious laws including the transfer of the Mithridatic command to Marius (Sull.
Principal wars: Social War (91-88); Civil War (88-82); Sertorian War (80-72); Mithridatic War (75-65); Third Servile War (73-71); war against the pirates (67); Civil War (50-44).
Principal wars: Jugurthine War (112-105); Cimbri and Teutones (105-101); Social War (91-88); First Mithridatic War (89-84); Roman Civil War (88-82).
Principal wars: war with Rome (93-92); war with Seleucia (83); wars in Syria, Cilicia, and Egypt (78-70); war with Rome (69-66)/Third Mithridatic War (75-65).