Several studies also unravel other miRNA expressions associated with ovarian cancers; for instance, miR-16, miR-20a, miR-21, miR-23a
, miR-23b, miR-27a, miR-93, miR-30c and miR-30d, and miR-30e-3p were found to be overregulated, whereas miR-10b, miR-26a, miR-29a, miR-99a, miR-100, miR-125a, miR-125b, miR-143, miR-145, miR-199a, miR-214, miR-22, and miR-519a have opposite expressions [124-126].
 Human skeletal/muscular cells HeLa cells let-7b miR-193b miR-328-5p let-7g miR-197 miR-494-3p miR-19b miR-199a-5p miR-513a-5p miR-20a miR-210 miR-638 miR-23a
miR-221 miR-1201 miR-23b miR-324-3p miR-1246 miR-24 miR-324-5p miR-1275 miR-34a miR-365 miR-1908 miR-92a miR-423-3p miR-1972 miR-93 miR-484 miR-1973 miR-103 miR-486-5p miR-1974 miR-106a miR-490-3p miR-1977 miR-107 miR-503 miR-1798 miR-125b miR-501-3p miR-125a-5p miR-532-3p miR-127-3p miR-542-5p miR-133b miR-574-3p miR-133a miR-598 miR-134 miR-720 miR-149 miR-1974 miR-151-5p miR-1979 miR-181a miR-675 * Barrey et al.
 have performed a miRNA metasignature in PDAC and defined a 10-miRNA (upregulated: miR-21, miR-23a
, miR-31, miR-100, miR-143, miR-155, and miR-221; down-regulated: miR-148a, miR-217, and miR-375) metasignature for PDAC diagnosis.
discovered 9 upregulated circulating miRNAs (miR-21, miR-23a
, miR-24, miR-93, miR-100, miR-122a, miR-124a, miR-125b, and miR-148a) that could significantly distinguish between serum samples of osteoporotic and nonosteoporotic fractured patients in a cohort of 30 subjects per group .
These mRNAs are potential targets for previously identified PCa-deregulated miRNAs miR-15b, miR-20a, and miR-148a (DEDD), miR-20a and miR-21 (TNFRSF10B), miR-24, and -29a/b (TP53INP1), miR-29a/b (SPARC), miR-15b, miR-200c, and miR-375 (ABI2), and miR-23a
AKT2 mRNA reduction was correlated to reduced expression of miR-23a
and miR107 after loss of weight in obese dogs , suggesting an unexpected and incomprehensible increasing of AKT2 in the obese insulin resistant dogs before the weight loss.
They identified five distinctly expressed miRNAs (miR-146a, miR-21, miR-374, miR-29a* and miR-23a
), which are involved in regulating several important innate immune and antiviral pathways.
We also validated the downregulation of miR-124, miR-204-5p, miR-139-5p, miR-141, and miR-199a and the upregulation of miR-23a
in kidney cancer compared to normal tissue (see online Supplementary Fig.
In recent studies (57-59) the mirRNA expression pattern (known for its tissue and cell type specificity) in endothelial cells has been demonstrated to include let-7b, miR-16, miR-21, miR-23a
, miR-29, mi.R-100, miR-221, and miR-222.
Expression of 10 miRNAs was significantly lower in plasma from NR-[t.sub.0] versus R-[t.sub.0] (Table 4, Figure 4(a)); these included three miRNAs of particular interest: let-7d, miR223, and miR-23a
, whose expression was reported to be downregulated in T2D patients when compared to healthy individuals [6, 12, 25, 26].