The show's three hour and 17 minute length (minus end
credits) still felt like progress.
The two opposite poles of the cell are classified as the minus end
and plus end (Goshima et al., 2005).
After several decades of steadily mounting evidence, we have become quite aware that high airway pressures coupled with high airway driving pressures (end-inspiratory minus end
expiratory static airway pressure) may inflict ventilator induced lung injury (VILI).
Dyneins, members of a family of proteins known as motor molecules, then attach to the microtubules and travel to one end, known as the minus end.
Leaving the plus ends at the center of the cell, the dyneins pull the minus ends to either side of the beads.
Analysis of the time-lapse images revealed that microtubules add subunits to their plus ends while losing subunits from their minus ends
near the spindle poles.
For minus ends, the intermediate phase quickly switches back to the growth phase (2).
The behavior of severed minus ends of MAPs-bound microtubules was similar to that of severed minus ends of purifiedtubulin microtubules: they quickly switched from the intermediate phase back to the growth phase.