minor response


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minor response

In cancer care, a reduction in tumor size by less than 50% but more than 25%.
See also: response
References in periodicals archive ?
Best Response Number of Patients (%) Complete response 0 (0%) Partial response 1 (11%) Minor response (SD) 1 (11%) Non-evaluable 2 (22%) Progressive disease 5 (55%) Overall response rate 2 (22%) Table 3.
In an intermittent oral dosing study, OSI-906 was well-tolerated up to doses of 450mg and has provided preliminary evidence of anti-tumor activity, with one confirmed partial response in an adrenocortical carcinoma (ACC) patient; one minor response in a patient with non-small cell lung cancer (NSCLC); 14 patients with stabilization of their disease for longer than 12 weeks including 7 patients with stabilization of their disease for longer than 24 weeks (out of 27 patients evaluable for tumor response to date).
One patient with advanced solid tumors with brain metastases, who achieved a minor response, showed significant improvement in memory, processing speed and executive function after six, 12 and 24 weeks of therapy.
Four (20%) patients achieved a complete response (CR), two (10%) a very good partial response, six (30%) a partial response (PR) and five (25%) a minor response (MR).