minor malformation

minor malformation

A near-extinct term for any structural defect that does not cause significant clinical disease, functional abnormalities or cosmetic problems.
References in periodicals archive ?
Malformations were divided into major and minor; major malformation interferes considerably with the function of the child, minor malformation gives no serious medical or cosmetic consequences to the patients.
Minor malformation is defined as structural abnormality present at birth which has minimal effect on clinical function, but may have a cosmetic effect e.
There was no evidence that this use was associated with large categories of major or minor malformations.
A meta-analysis reported that SSRIs do not increase the risk of major malformations, cardiovascular malformations, or minor malformations but that they do increase the risk of spontaneous abortions (7).
The presence of other major and minor malformations in association with a cleft implies that a single etiologic factor--genetic, chromosomal or teratogenic--produced the pattern as a whole.
A great number of major and minor malformations occur in this area, for instance cleft palate, the glubulomaxillary cyst and missing or supernummary and peg shaped lateral incisors.
Among the minor malformations, we found a five times higher rate of angioma, benign tumours made up of small blood vessels on or near the surface of the skin.
Jones reported that 26% of children exposed to phenytoin were rated as affected with features of the anticonvulsant facies based on ratings of minor malformations, compared with 24% of those exposed to phenobarbital and only 3% of those exposed to carbamazepine.
Even though these three drugs probably are low-risk, there have been some reports of minor malformations with prolonged use of fluconazole and itraconazole, and data are lacking for terbinafine.
In the echinacea group, six major and six minor malformations occurred; of these, four major and two minor malformations appeared in babies of women who took echinacea during the first trimester, the most important period in terms of initial fetal development.
These data include a 1997 study of pregnant women that found no significant difference in the rates of major or minor malformations, gestational age at delivery birth weight, or neonatal distress among 39 women who took cetirizine (most included first-trimester use), 81 women who took hydroxyzine (Vistaril or Atarax), and 110 controls who did not take either agent.
In addition, in the babies of the exposed versus the controlled group, the incidence of minor malformations was 5 to 1, neonatal eczema 12 to 2 and premature births 9 to 3.