Pleasure noted that considerable research interest has arisen about the use of minocycline
for diseases of the central nervous system because of the increasing evidence about its neuroprotective effects.
Evaluation of in-vitro activity of new quinolones, macrolides, and minocycline
against Mycoplasma pneumoniae.
(14) found that minocycline
increased the life span and motor activity and decreased MDA formation of manganese treated D.
has an even higher lipid solubility; human clinical results suggest that it should prove a suitable, if expensive, alternative to doxycycline for treating tick-borne diseases.
(1) To test the hypothesis that subjects with acute stroke treated with IV minocycline
and tPA have fewer intracranial haemorrhages (ICH) compared with those treated with IV tPA and standard care, seen on routine followup CT scans, 24 [+ or -] 8 hours posttreatment.
Schlichter, "Evolution of the inflammatory response in the brain following intracerebral hemorrhage and effects of delayed minocycline
treatment," Brain Research, vol.
Hospital Medical Center initiated a study looking at the effects of minocycline
treatment on ASD symptoms.
Repurposing an old drug to improve the use and safety of tissue plasminogen activator for acute ischemic stroke: minocycline
. Rev Neurol Dis.
Separate formulations of topical minocycline
are in development for acne and rosacea.
While MM has been used during PMT since the early 2000's, most studies have investigated clinical outcomes following the application of minocycline
microspheres during initial SRP.
9,918,998), entitled Pharmaceutical Tetracycline Composition For Dermatological Use, covers a topical composition comprised of minocycline
or another tetracycline-class drug and a method for making such compositions.
is a second-generation semi-synthetic broad-spectrum bacteriostatic tetracycline antibiotic.