minocycline


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minocycline

 [mĭ-no-si´klēn]
a semisynthetic broad-spectrum antibiotic of the tetracycline group; administered orally or intravenously as the hydrochloride salt

minocycline

(mĭn′ə-sī′klēn′, -klĭn)
n.
A broad-spectrum antibiotic, C23H27N3O7, derived from tetracycline and used usually in the form of its hydrochloride.

minocycline

A broad-spectrum tetracycline which has a longer serum half-life and achieves higher serum levels than simple tetracycline.

Indications
Acne, Lyme disease, MRSA, and other resistant microbes; it is also a recognised disease-modifying anti-rheumatic drug (DMARD).

Adverse effects
Vertigo, diarrhoea, patchy skin pigmentation, autoimmune disease.

minocycline

A TETRACYCLINE antibiotic used to treat ACNE and general infections. Brand names are Aknemin and Minocin.
References in periodicals archive ?
Pleasure noted that considerable research interest has arisen about the use of minocycline for diseases of the central nervous system because of the increasing evidence about its neuroprotective effects.
Evaluation of in-vitro activity of new quinolones, macrolides, and minocycline against Mycoplasma pneumoniae.
(14) found that minocycline increased the life span and motor activity and decreased MDA formation of manganese treated D.
Minocycline has an even higher lipid solubility; human clinical results suggest that it should prove a suitable, if expensive, alternative to doxycycline for treating tick-borne diseases.
(1) To test the hypothesis that subjects with acute stroke treated with IV minocycline and tPA have fewer intracranial haemorrhages (ICH) compared with those treated with IV tPA and standard care, seen on routine followup CT scans, 24 [+ or -] 8 hours posttreatment.
Schlichter, "Evolution of the inflammatory response in the brain following intracerebral hemorrhage and effects of delayed minocycline treatment," Brain Research, vol.
Hospital Medical Center initiated a study looking at the effects of minocycline treatment on ASD symptoms.
Repurposing an old drug to improve the use and safety of tissue plasminogen activator for acute ischemic stroke: minocycline. Rev Neurol Dis.
Separate formulations of topical minocycline are in development for acne and rosacea.
While MM has been used during PMT since the early 2000's, most studies have investigated clinical outcomes following the application of minocycline microspheres during initial SRP.
9,918,998), entitled Pharmaceutical Tetracycline Composition For Dermatological Use, covers a topical composition comprised of minocycline or another tetracycline-class drug and a method for making such compositions.
Minocycline is a second-generation semi-synthetic broad-spectrum bacteriostatic tetracycline antibiotic.