(redirected from mink encephalopathy)
Also found in: Dictionary, Thesaurus, Encyclopedia.


A gene on chromosome 21q22.12 that encodes a member of the KCNE K+ channel family, which are essential to many cellular functions; they are protean in their electrophysiologic and pharmacologic properties. The KCNE1 protein product associates with the KVLQT1 protein product forming the delayed rectifier potassium channel.

Molecular pathology
KVLQT1 mutations are associated with Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome.
References in periodicals archive ?
Transmissible mink encephalopathy (TME) is a rare prion disease in ranch-raised mink (Mustela vison) in North America and Europe (1-4).
Clinical and morphological investigation of transmissible mink encephalopathy. Vopr Virusol.
This situation may be similar to that of mink that have mink encephalopathy in which infection of peripheral lymphoid and other tissues is seen only when the animals are in the late stages of disease.
Nonetheless, infectivity has been found previously in salivary glands of mice after injection of infected tissues with a high titer of scrapie agent (32) and of mink injected with the transmissible mink encephalopathy agent (33).
In addition to BSE, the book contains chapters about TSE of North America such as scrapie, transmissible mink encephalopathy, and chronic wasting disease of deer and elk; the last disease has recently spread from its endemic Colorado-Wyoming area to six other states in the United States, as well as Alberta and Saskatchewan in Canada.