minimum bactericidal concentration


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Related to minimum bactericidal concentration: Minimum inhibitory concentration

minimum bactericidal concentration

The lowest concentration of an antibiotic that is bactericidal to ≥ 99.9% of an original inoculum.

MBC is a form of antibiotic susceptibility testing in which an antimicrobial agent in broth is serially diluted, or titrated in a standardised (McFarland) suspension of bacteria; tubes in which there is no growth are subcultured in an antibiotic-free growth medium. The MBC may vary as a function of certain intrinsic features of the bacterium.

minimum bactericidal concentration

Lab medicine The lowest concentration of an antibiotic that is bactericidal to ≥ 99.9% of an original inoculum. See Persistence phenomenon, Paradoxic effect, and Tolerance.

minimum bactericidal concentration

The lowest concentration of an antimicrobial that kills a defined fraction of bacteria or fungi.
Synonym: minimum lethal concentration
See also: concentration
References in periodicals archive ?
Table 4: Qualitative Minimum Inhibition Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of Coleus ambonicus crude methanolic (CACM) leave extract against MRSA clinical isolates.
Discrepancy between minimum inhibitory and minimum bactericidal concentrations of penicillin for group A and group B [beta]-hemolytic streptococci.
The minimum bactericidal concentration value was determined for same test tubes after 3 days incubation time through changes in the turbidity.
coli, MIC: minimum inhibitory concentration, MBC: minimum bactericidal concentration, with *: bactericidal effects, and without *: bacteriostatic effects.
The minimum bactericidal concentration (MBC) values were determined by spreading 10 pl from each wells of MIC into Muller Hinton agar.
The minimum bactericidal concentration (MBC) for this study was 12.5% (0.125 g/mL) for both susceptible and resistant bacteria strains.
pyogenes + + 40 Table 4: Minimum Bactericidal Concentration (MBC) of the fractions against test organisms.
Keywords: Dodonaea viscosa, GC-MS analysis, Antimicrobial activity, Phytochemical investigation, Minimum Bactericidal concentration
The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of this extract for Streptococcus sanguinis were 6.25 mg/mL and 25 mg/mL, respectively, which were the lowest MIC and MBC values.
A minimum bactericidal concentration (MBC) is the lowest concentration of an antibiotic required to kill a microorganism.
helioscopia via agar well diffusion method for determining antibacterial activity and activity index (AI) against two gram negative and two gram positive bacteria and broth macrodilution method to estimate quantitatively its minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) and bacteriostatic concentration.
Especially noteworthy was the activity against MRSA with a minimum inhibitory concentration (MIC) and a minimum bactericidal concentration (MBC) ranging from 0.39 to 0.78 [micro]g/ml.

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