minimally invasive autopsy

minimally invasive autopsy

A generic term for a postmortem examination in which there is minimal to no disruption of major body cavities, e.g., by using CT, MRI, laparoscopy and needle biopsies.

Minimally invasive autopsy formats
Minimally intrusive
• External examination only; 
• Patient history from clinician and examination of medical records;
• Verbal autopsy.

Imaging “autopsies”
• MRI autopsy;
• CT autopsy.

Minimally invasive
• Aspiration of blood, urine, cytology, etc., for analysis;
• Multiple percutaneous needle biopsies after death (“blind biopsies”);
• Lapraroscopic and thorascopic investigation with tissue sampling;
• Mini-autopsy—extensive organ sampling or removal via a limited incision (e.g., a 15-cm upper abdominal wall incision).
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"The development of a minimally invasive autopsy technique would reduce the overall number of invasive autopsies performed in the UK but would still provide a service to the Coroner and determine the cause of a person's death.
(8,22,23) Although Kelly initially garnered Osler's attention because of his radically innovative approach to performing a minimally invasive autopsy, Osler clearly recognized that Kelly was going to be an innovator for the rest of his career.
This edition includes papers on the teaching of pathology in the undergraduate curriculum, recent advances in work on primary carcinomas of the salivary glands, the intricacies of Barrett's esophagus, the concept of epithelial-mesenchymal transition in cancer invasion and metastasis, matrix metalloproteinases in neoplastic progression, new concepts of osteoarthritis, cutaneous pseudolymphoma, liquid-based cytology for cervical screening, pitfalls in the diagnosis of soft tissue tumors, sudden unexpected death in infancy, conducting the non-invasive or minimally invasive autopsy, and a histopathological view of bioterrorism.

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