minimal inhibitory concentration


Also found in: Dictionary, Thesaurus, Legal, Acronyms, Encyclopedia.
Related to minimal inhibitory concentration: Minimal Bactericidal Concentration

concentration

 [kon″sen-tra´shun]
1. increase in strength by evaporation.
2. the ratio of the mass or volume of a solute to the mass or volume of the solution or solvent.
3. intense mental focus.
hydrogen ion concentration see hydrogen ion concentration.
mass concentration the mass of a constituent substance divided by the volume of the mixture, as milligrams per liter (mg/l).
mean corpuscular hemoglobin concentration (MCHC) the average hemoglobin concentration in erythrocytes, conventionally expressed in “per cent,” meaning grams per deciliter of red blood cells, obtained by dividing the blood hemoglobin concentration (in g/dl) by the hematocrit (in l/l): MCHC = Hb/Hct.
minimal alveolar concentration (MAC) the concentration of anesthetic that at a pressure of 1 atmosphere produces immobility in 50 per cent of subjects exposed to a noxious stimulus.
minimal bactericidal concentration (MBC) the lowest concentration of a given antibiotic required to kill a specific organism.
minimal inhibitory concentration (MIC) the lowest concentration of a given antibiotic that inhibits the growth of a specific organism.
molar concentration the concentration of a substance expressed in terms of molarity.
concentration test a test of renal function based on the patient's ability to concentrate urine; see also fishberg concentration test.

min·i·mal in·hib·i·tor·y con·cen·tra·tion (MIC),

the lowest concentration of antibiotic sufficient to inhibit bacterial growth when tested in vitro.

minimal inhibitory concentration (MIC)

the lowest concentration of an antibiotic medication in the blood that is effective against a bacterial infection, determined by inoculating the bacteria into a culture medium containing various concentrations of a proposed antibiotic. The lowest antibiotic concentration that stops microbial growth may be used in further treatment of the patient. Also called minimum inhibitory concentration. Compare minimal bactericidal concentration.

min·i·mal in·hib·i·tor·y con·cen·tra·tion

(MIC) (mini-măl in-hibi-tōr-ē kon'sĕn-trāshŭn)
Lowest concentration of antibiotic sufficient to inhibit bacterial growth when tested in vitro.
References in periodicals archive ?
Sessile minimal inhibitory concentrations 50 and 80 (SMIC50 and SMIC80, respectively) were defined as the drug concentrations at 50 and 80% decreases in absorbance (Pierce et al.
The Minimal Inhibitory Concentration (MIC) test was performed by using the microdilution broth method, following the recommendations established by CLSI (2010), with some modifications.
The mean time that salivary concentrations of miconazole were above the minimal inhibitory concentration level needed to treat the infection was 7 hours for the tablet compared with 1.
The antimicrobial activity was estimated by determination of the minimal inhibitory concentration by the broth microdilution method.
The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC), the rate of kill and the pH sensitivity of the essential oil were determined by microdilution tests performed in 96-well plates.
Minimal inhibitory concentration (MIC) was defined as the lowest concentration of antibiotics inhibiting the visible growth of the test strain in g/ml (Table 2).
Muller-Hinton broth (MHB) or Luria-Bertani broth (LB) was used for minimal inhibitory concentration (MIC) tests, and bacterial cultures were maintained at 37 [degrees] C for 18-20 h.
A macrodilution broth method was used to determine the minimal inhibitory concentration (MIC), according to NCCLS reference documents M38P (1998).
A sensitive and quick microplate method to determine the Minimal Inhibitory Concentration of plant extracts for bacteria.
parasiticus 16 32 8 8 MIC = minimal inhibitory concentration, MLC = minimal lethal concentration
The lowest concentration of compound showing no growth was taken as its minimal inhibitory concentration (MIC).
Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) of ethanolic extract from Rhodomyrtus tomentosa on some pathogenic bacteria.

Full browser ?