minimal inhibitory concentration

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Related to minimal inhibitory concentration: Minimal Bactericidal Concentration


1. increase in strength by evaporation.
2. the ratio of the mass or volume of a solute to the mass or volume of the solution or solvent.
3. intense mental focus.
hydrogen ion concentration see hydrogen ion concentration.
mass concentration the mass of a constituent substance divided by the volume of the mixture, as milligrams per liter (mg/l).
mean corpuscular hemoglobin concentration (MCHC) the average hemoglobin concentration in erythrocytes, conventionally expressed in “per cent,” meaning grams per deciliter of red blood cells, obtained by dividing the blood hemoglobin concentration (in g/dl) by the hematocrit (in l/l): MCHC = Hb/Hct.
minimal alveolar concentration (MAC) the concentration of anesthetic that at a pressure of 1 atmosphere produces immobility in 50 per cent of subjects exposed to a noxious stimulus.
minimal bactericidal concentration (MBC) the lowest concentration of a given antibiotic required to kill a specific organism.
minimal inhibitory concentration (MIC) the lowest concentration of a given antibiotic that inhibits the growth of a specific organism.
molar concentration the concentration of a substance expressed in terms of molarity.
concentration test a test of renal function based on the patient's ability to concentrate urine; see also fishberg concentration test.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

min·i·mal in·hib·i·tor·y con·cen·tra·tion (MIC),

the lowest concentration of antibiotic sufficient to inhibit bacterial growth when tested in vitro.
Farlex Partner Medical Dictionary © Farlex 2012

min·i·mal in·hib·i·tor·y con·cen·tra·tion

(MIC) (mini-măl in-hibi-tōr-ē kon'sĕn-trāshŭn)
Lowest concentration of antibiotic sufficient to inhibit bacterial growth when tested in vitro.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
However, [MIC.sub.50] and [MIC.sub.90] in the isolates evaluated in this study were 0.06 [micro]g/ml and 0.125 [micro]g/ml, respectively, which was significantly lower than minimal inhibitory concentrations detected in our study.
% Pre-analytic phase Information system interfaced with hospital for 110 23.6 online results (466) Equipment Automated system for blood culture (467) 202 43.3 Automated system for identification and 177 37.9 susceptibility testing (467) Automated system for mycobacteria (466) 37 7.9 Automated system for fungal identification (394) 83 21.1 Procedures Bacterial typing (467) 52 11.1 Minimal inhibitory concentration determination (467) 184 39.4 Susceptibility testing for nonstandard drugs (465) 195 41.9 Antifungal susceptibility testing (466) 41 8.8 Post-analytic phase Important strains are stored (458) 139 30.3 (a) Number of laboratories that provided answers to the corresponding survey questions.
With the agar disc diffusion assay, oils were found to be active Escherichia coli, Pseudomonas aeroginosa, Staphylococcus aureus and Staphylococcus intermedius at a minimal inhibitory concentration (MIC) of 0.25, 0.98 0.68 mg/mL and 1.25 mg/mL.
This test correlates well with microtiter broth dilution minimal inhibitory concentrations and has the advantage of providing data on a continuous scale rather than the 2-fold dilution format of microtiter assays.[14,15] The susceptibility of each isolate to penicillin, trimethoprim-sulfamethoxazole, erythromycin, tetracycline, vancomycin, and cefotaxime was tested.
As mentioned earlier minimal inhibitory concentration against most susceptible mycobacterium is 0.5 [micro]g/mL, was found to be present in saliva and serum in both group I and group II subjects.
The minimal inhibitory concentration for sessile cells (SMIC) was defined as the concentration of antifungal that caused a 50% (SMIC 50) and 80% (SMIC 80) reduction of treated biofilms.
The study that were done on microsporium gypseum and trichophyton mentagrophytes in india has shown that cysteine hydrochloride amino acids and aspartic acid have inhibitory effect and minimal inhibitory concentration of cysteine hydrochloride for microsporium gypseum is 0.5 gr/dl and for trichophyton mentagrophytes is 0.4 gr/dl were reported.
Minimal inhibitory concentration (MIC) of antibiotics and the effect of combinations with ethanolic extract of H.
Purified cPA (>99%) yielded typical minimal inhibitory concentration (MIC) values of 10-20 microg/ml against gram-positive bacteria.
The most accurate form of antimicrobial susceptibility testing for staphylococci is a minimal inhibitory concentration method (broth dilution, agar dilution, or agar-gradient diffusion) using a full 24-hour incubation.
For each of them the minimal inhibitory concentration was calculated.

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