minimal inhibitory concentration


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Related to minimal inhibitory concentration: Minimal Bactericidal Concentration

concentration

 [kon″sen-tra´shun]
1. increase in strength by evaporation.
2. the ratio of the mass or volume of a solute to the mass or volume of the solution or solvent.
3. intense mental focus.
hydrogen ion concentration see hydrogen ion concentration.
mass concentration the mass of a constituent substance divided by the volume of the mixture, as milligrams per liter (mg/l).
mean corpuscular hemoglobin concentration (MCHC) the average hemoglobin concentration in erythrocytes, conventionally expressed in “per cent,” meaning grams per deciliter of red blood cells, obtained by dividing the blood hemoglobin concentration (in g/dl) by the hematocrit (in l/l): MCHC = Hb/Hct.
minimal alveolar concentration (MAC) the concentration of anesthetic that at a pressure of 1 atmosphere produces immobility in 50 per cent of subjects exposed to a noxious stimulus.
minimal bactericidal concentration (MBC) the lowest concentration of a given antibiotic required to kill a specific organism.
minimal inhibitory concentration (MIC) the lowest concentration of a given antibiotic that inhibits the growth of a specific organism.
molar concentration the concentration of a substance expressed in terms of molarity.
concentration test a test of renal function based on the patient's ability to concentrate urine; see also fishberg concentration test.

min·i·mal in·hib·i·tor·y con·cen·tra·tion (MIC),

the lowest concentration of antibiotic sufficient to inhibit bacterial growth when tested in vitro.

minimal inhibitory concentration (MIC)

the lowest concentration of an antibiotic medication in the blood that is effective against a bacterial infection, determined by inoculating the bacteria into a culture medium containing various concentrations of a proposed antibiotic. The lowest antibiotic concentration that stops microbial growth may be used in further treatment of the patient. Also called minimum inhibitory concentration. Compare minimal bactericidal concentration.

min·i·mal in·hib·i·tor·y con·cen·tra·tion

(MIC) (mini-măl in-hibi-tōr-ē kon'sĕn-trāshŭn)
Lowest concentration of antibiotic sufficient to inhibit bacterial growth when tested in vitro.
References in periodicals archive ?
Sessile minimal inhibitory concentrations 50 and 80 (SMIC50 and SMIC80, respectively) were defined as the drug concentrations at 50 and 80% decreases in absorbance (Pierce et al.
The study that were done on microsporium gypseum and trichophyton mentagrophytes in india has shown that cysteine hydrochloride amino acids and aspartic acid have inhibitory effect and minimal inhibitory concentration of cysteine hydrochloride for microsporium gypseum is 0.
The results of the studies, a research collaboration between Sequella and Tibotec, demonstrated that the combination of SQ109 with TMC207 decreased the TMC207 minimal inhibitory concentration (MIC) by 4- to 8-fold for the etiologic agent of TB, Mycobacterium tuberculosis.
Minimal inhibitory concentration (MIC) of antibiotics and the effect of combinations with ethanolic extract of H.
Purified cPA (>99%) yielded typical minimal inhibitory concentration (MIC) values of 10-20 microg/ml against gram-positive bacteria.
Interpretive minimal inhibitory concentration (MIC) breakpoints and MIC ranges for QC isolates are summarized in Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Third Informational Supplement, which is also now available from CLSI.
Acetone and methanol crude extracts exhibited the best antimicrobial activity with minimal inhibitory concentration (MIC) of 0.
The study that were done on microsporium gypseum and epidermophyton floccosum in India has shown that cysteine hydrochloride amino acids and aspartic acid have inhibitory effect and minimal inhibitory concentration of cysteine hydrochloride for microsporium gypseum is 0.

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