midazolam


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midazolam

 [mid-az´o-lam]
a sedative of the benzodiazepine class used in the induction of anesthesia.

midazolam

/mid·azo·lam/ (mid´a-zo-lam″) a benzodiazepine tranquilizer, used as the maleate ester for sedation and in the induction of anesthesia.

midazolam

(mĭ-dăz′ə-lăm′)
n.
A benzodiazepine drug, C18H13ClFN3, primarily used in its hydrochloride form as a sedative and antianxiety agent before surgery and before or during medical procedures.

midazolam

Versed® Pharmacology A short-acting anxiolytic, hypnotic anticonvulsant Indications IV sedation, general anesthesia, therapeutically refractory status epilepticus, muscle relaxing Adverse effects Ataxia, incoordination, mental and psychomotor impairment, confusion, dysarthria, retrograde amnesia, paradoxical effects; rarely, N&V, venous complications. See Phenytoin, Seizure, Status epilepticus.

midazolam

A BENZODIAZEPINE drug given by intravenous injection as a sedative for minor surgery or to induce general anaesthesia. A brand name is Hypnovel.
References in periodicals archive ?
Oklahoma started using midazolam because companies making traditional barbiturates, which have a longer track record and deeper anesthetic properties, have refused to provide them for executions.
In contrast to findings in the other national surveys, [7-12] midazolam was the preferred sedative in this SA study.
For example, studies have concluded that seizure cessation was faster with diazepam, but the time to administer IV diazepam was greater than intranasal midazolam (Javadzadeh et al.
As the only podiatric (surgery) centre in the UK using the technique up until 2013, without an anaesthetist's direct support (anaesthetic sessions are however supported by trained staff in the monitoring of patients), the team sought information that would allow informed reflection on the beneits and effects of midazolam on known measureable parameters routinely used in our theatre.
The hydroxylation of midazolam, reactions considered to be CYP3A-mecliated in the human (CYP3A4) and rat (CYP3A1/2), leads to the major metabolite 1'-hydroxy midazolam (Chovan et al.
The intraoperative VAS was significantly less in magnesium and midazolam groups compared to control group after 15 and 30 minutes (Figure 3).
Patients receiving less midazolam may have received high-dose opiates causing prolonged ventilation.
Na comparacao entre momentos, a FC foi superior aos 5 e 10 minutos em relacao aos 20 e 30 minutos apos o inicio da infusao de midazolam ou midazolam/fentanil (Tabela 2).
19) In a recent study, propofol was compared with midazolam in endoscopies, as far as sedation and early recovery propofol is more effective as compare to midazolam.
Midazolam, a water soluble benzodiazepine, produces an analgesic action through the benzodiazepine/gamma aminobutyric acid (GABA) receptor complex in the spinal cord.
The findings indicated that within 24 hours, the ketamine group had a clinically significant reduction in suicidal thoughts that was greater than with the midazolam group.
The ketamine group showed an overall improvement in their mood, depression and fatigue as compared to the midazolam group, the report added.