Histopathology, Immunohistochemistry, and Molecular Characteristics.--Most duodenal hyperplastic polyps reported so far in the literature (14 of 16 cases; 87.5%) have the histologic appearance of a microvesicular
hyperplastic polyp of the large bowel, characterized by hyperplastic, columnar microvesciular mucinous epithelium with luminal and crypt serration lacking cytologic atypia (Figure 4, A).
In comparison to normal control all the liver showed fatty infiltration, both microvesicular
and macrovesicular steatosis that was in ordinance to high fructose diet as apparent in prior studies.
steatosis was noted in approximately 80% of the liver core.
Liposomes are nanovesicular or microvesicular
drug or gene delivery systems which range in size from 0.025 to 10 [mu]m and contain a single lipid bilayer or multiple interwoven lipid bilayers.
These case studies are focused on read-across of (un-)branched carboxylic acids for the prediction of microvesicular
liver steatosis (CS-1); on the effects of valproic acid analogues regarding their developmental and reproductive toxicity (CS-2); on mitochondrial toxicity effects regarding repeated dose toxicity and developmental and reproductive toxicity (CS-4); and CS-8 is focused on read-across of diketones as the trigger for the 'Popcorn Lung'.
reported a rate of 62% microvesicular
and 38% macrovesicular steatosis in liver allografts from deceased donors from 2001 to 2007 in Australia .
The model of fructose-iron showed evidence of mild to moderate deposition of macrovesicular and microvesicular
fat with minimal signs of perisinusoidal fibrosis in 3 of 12 rats.
Microscopic observation of the H and E stained liver sections of the untreated alloxan induced diabetic rats showed very early microvesicular
fatty change in the centrilobular areas of the liver tissue, mild congestion, moderate lymphocytic infiltrates mostly around portal tract, focal necrosis with inflammatory cell infiltrates, and focal fibrosis (Figure 1(b)).
Keski-Oja, "Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular
exosomes," Journal of Cellular Biochemistry, vol.
The liver biopsy results showed mild macrovesicular and microvesicular
steatosis with mild portal and lobular inflammation.
Grade 3 macro- and microvesicular
diffuse steatosis was present in 60% of the hepatocytes.
Wieser et al., "Secreted microvesicular
miR-31 inhibits osteogenic differentiation of mesenchymal stem cells," Aging Cell, vol.