The Generx, alferminogene tadenovec [Ad5FGF-4] Phase 3 product candidate, is a first in class, single-dose, disease altering therapeutic, specifically targeted for the cardiac micro-vasculature, that is designed to leverage cardiac plasticity to stimulate and augment the formation of new coronary structures in patients with cardiac microvascular
insufficiency (CMI) and coronary artery disease.
Dilaforette is a Swedish drug development company developing sevuparin, an innovative, proprietary polysaccharide drug, which has potential to restore blood flow and prevent further microvascular
obstruction in both sickle cell disease and malaria patients.
If you are suspected of having Secondary Raynaud's, you will be referred to a Consultant and then the Freeman Hospital's Microvascular
Measurement Service for tests.
1c] across the 2 treatment arms did not produce similar reductions in incident microvascular
For a given age group, the rates of each outcome, particularly hypoglycaemia and microvascular
complications, increased dramatically with longer duration of the disease.
The new findings not only help explain the molecular mechanisms underlying microvascular
disease in diabetes patients, they also suggest that because PGC-1alpha has opposing effects in different cell types, its role as a potential new therapeutic target should be pursued with caution.
The findings, which were published in the American Journal of Psychiatry, are consistent with a growing body of evidence for the connection between microvascular
issues and schizophrenia.
The findings suggest that "the presence of these retinal microvascular
changes is indicative of additional vascular risk beyond that conferred by traditional cardiovascular risk factors," the investigators said.
decompression for GPN is associated with high rates of pain relief (80%-90%) (9, 11, 12).
Several studies demonstrated the relationship between MS and coronary microvascular
The aim of the present study was to assess the effects of intravenously and topically applied pLc on microvascular
permeability increase induced by I/R in the hamster cheek pouch preparation.
Otolaryngology-head and neck surgeons from the US describe oromandibular and palatomaxillary complex reconstruction; oral cavity, cheek, neck, pharynx, cervical esophagus, hypopharynx, skull base, and scalp reconstruction; management of the paralyzed face; and pediatric and microvascular