LC3B (microtubule-associated proteins
1A/1B light chain 3B), another human LC3 gene family member, was stained positive in 63 out of 117 (53.8%) samples.
Tau protein plays an important role as a microtubule-associated protein
in neuronal axons, stabilizing microtubules and inducing their assembly .
In the present study, we focus on the microtubule-associated protein
tau in development, degeneration and protection of neurons.
These seeding microtubule fragments should have retained a high level of microtubule-associated proteins
. It is thus assumed that [C.sub.c] [approximately equal to] 2 [micro]M in .
Cohen, "Phosphorylation of microtubule-associated protein
tau by stress-activated protein kinases," FEBS Letters, vol.409, no.
Other neuronal marker proteins that have been identified in central neurocytoma include neurofilament protein, neuron-associated class III [beta]-tubulin, and microtubule-associated proteins
MAP2 and tau.
In addition, phosphorylation of microtubule-associated proteins
(MAPS) and actin-associated proteins may induce alterations of polymerization of MTs and distribution of MFs (30,31).
(MAPs) have many subtypes, including MAP1A, MAP1B, MAP2, MAP4, and tau proteins.
JNK exerts its effects on the cytoskeleton by phosphorylating numerous microtubule-associated proteins
(MAPs) such as MAP2, MAP1B, tau and the stathmin family microtubule-destabilizing protein SCG10.
On the molecular level, plectin binds to a variety of cytoskeletal proteins, including cytoplasmic and nuclear IF subunit proteins (vimentin, GFAP, cytokeratins, neuro-filament proteins, lamin B), subplasma membrane proteins (fodrin and [Alpha]-spectrin), and high molecular weight microtubule-associated proteins
MAP1 and MAP2 (Herrmann and Wiche, 1987; Foisner et al., 1988; Wiche et al., 1993).
Such a bundling mechanism can be applied to a class of cationic actin-bundling proteins, including smooth muscle calponin and the microtubule-associated proteins
tau and Map2c.