The results showed that Dahuang was able to improve blood perfusion and oxygen supply of the intestinal mucosa in sepsis settings by dilating capillaries of the intestinal mucosa, reducing the formation of microthrombus
, protecting endothelial cells of the intestinal mucosal capillaries, and increasing the number of functional intestinal mucosal capillaries.
Lacunar infarct occurs due to occlusion caused by a microthrombus
or lipohyalinosis in a penetrating artery in the basal ganglia, thalamus, and pons.
The occurrence of microthrombus
is one of the key reasons of no-reow" phenomenon.
2, part B), microthrombus
formation and presence apoptotic body in the G2 and G3 groups, and more apoptotic bodies were found in the G3 group than in the G2 group.
However, presence of microthrombus
is found with a high rate on autopsies.
The study has also proved there is some effect in the coagulation and microthrombus
during the sepsis , which is equal to the cross talk of inflammation and coagulation in the process of sepsis.
Presence of a microthrombus
in the coronary capillaries plays a crucial role in the slow- or no-reflow phenomenon after AMI (23).
Review of the corresponding hematoxylin-eosin sections revealed that these areas were sites of prior biopsy or microthrombus
formation (Figure 9, A through E).
If used with certain energy-promoters, marked pharmacological effects may develop including antagonizing shock-induced drop of blood pressure, reducing endotoxin-induced declination of plasma viscosity, disturbing the formation of microthrombus
and eliminating the obstruction by plates and leukocytic aggregation.