microsome

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microsome

 [mi´kro-sōm]
any of the vesicular fragments of endoplasmic reticulum produced during disruption and centrifugation of cells. adj., adj microso´mal.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

mi·cro·some

(mī'krō-sōm),
One of the small spheric vesicles derived from the endoplasmic reticulum after disruption of cells and ultracentrifugation.
[micro- + G. sōma, body]
Farlex Partner Medical Dictionary © Farlex 2012

microsome

Any of a heterogeneous group of variably sized and shaped, closed lipoprotein-rich vesicles, which are formed from ruptured endoplasmic reticulum and large polyribosomes when a cell is ultracentrifuged at 100,000 g for 60 minutes.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

mi·cro·some

(mī'krō-sōm)
One of the small spheric vesicles derived from the endoplasmic reticulum after disruption of cells and ultracentrifugation.
[micro- + G. sōma, body]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

microsome

see MICROSOMAL FRACTION.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Odani, T Kawai et al., "Pharmacological characterization of diethyl-2-({3-dimethyl carbamoyl-4-[(4,-trifluoromethylbiphenyl-2-carbonyl) amino] phenyl}acetyloxymethyl) -2-phenylmalonate (JTT-130), an intestine-specific inhibitor of microsomal triglyceride transfer protein," Journal of Pharmacology and Experimental Therapeutics, vol.
Wainer, "High-performance liquid chromatography assay for simultaneous determination of dextromethorphan and its main metabolites in urine and in microsomal preparations," Journal of Chromatography B, vol.
The cytosolic proteins can act as acceptors for fatty acids but not for phospholipids of microsomal origin.
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1.
Serum gonadotrophins, fasting serum insulin and serum thyroid microsomal antibodies were recorded.
Gene Gene name US patent symbol MGST3 Microsomal glutathione S-transferase 3 5,919,627 GBP1 Guanylate binding protein 1, interferon- 6,894,157 inducible, 67kDa GGH Gamma-glutamyl hydrolase (conjugase, 5,801,031 folylpolygammaglutamyl hydrolase) MTAP Methylthioadenosine phosphorylase 5,942,393; 6,870,037 MADCAM1 Mucosal vascular addressin cell adhesion 7,750,137 molecule 1 POSTN Periostin, osteoblast specific factor 6,518,063 PMS1 PMS1 postmeiotic segregation increased 1 5,922,855; (S.
Summary: Neurotech Pharmaceuticals Announces Initiation of Phase 1 Clinical Trial for AAD-2004, a Potent Spin Trapping Molecule and Microsomal Prostaglandin E Synthase-1 Inhibitor, Targeting Alzheimer's, Parkinson's, and Lou Gehrig's Disease
Drug clearance is predicted in vitro using rat and human microsomal stability assays, but the Metasite tool is plugged into ESMA and allows chemists to quickly assess likely metabolic weak points on their molecules, which they should seek to address.
Laboratory results pre-operatively Patient Results Normal Values TSH 0.010 IU/mL 0.47 - 5.04 IU/mL TSH 0.0004 IU/mL 0.47 - 5.04 IU/mL Free T3 3.4 pg/mL 1.5 - 3.5 pg/mL T4 13.52 mg/dL 4.5 - 12.0 mg/dL Thyroglobulin 124.0 ng/mL 0.5 - 5.5ng/mL Thyroid Stimulating 211% 0 - 125% Immunoglobulin Microsomal Antibodies 16.77 IU/mL Negative less than 40 Thyroglobulin Antibodies Less than 33.3 IU/mL Negative less than 79 Table 2.

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