microscopic polyangiitis

(redirected from microscopic polyarteritis nodosa)

microscopic polyangiitis

systemic, nongranulomatous small-vessel vasculitis, associated with glomerulonephritis, pulmonary capillaritis, palpable purpura, and antineutrophil cytoplasmic autoantibodies.
Farlex Partner Medical Dictionary © Farlex 2012

microscopic polyangiitis

A systemic small-vessel vasculitis that primarily affects the kidneys, skin, and lungs of middle-aged men.

Clinical findings
Fever, malaise, myalgia, weight loss, and autoimmunity, including antineutrophil cytoplasmic antibodies (p-ANCA). Skin lesions occur in 30 to 50%, usually presenting as purpura due to leukocytoclastic vasculitis, less commonly as nodules involving the vessels of the dermis and subcutaneous fat and ulcers. The kidney shows rapidly progressive focal and segmental glomerulonephritis.

DiffDx
Polyarteritis nodosa.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

microscopic polyangiitis

Hypersensitivity angiitis, microscopic periarteritis, microscopic polyarteritis Internal medicine The term recommended for necrotizing vasculitis with few or no immune deposits, affecting small vessels–ie, arterioles, capillaries, venules; MP is often accompanied by ANCA, necrotizing glomerulonephritis and pulmonary capillaritis. See Small vessel vasculitis, Systemic vasculitis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

mi·cro·scop·ic pol·y·an·gi·i·tis

(mī'krŏ-skop'ik pol'ē-an'jē-ī'tis)
Systemic, nongranulomatous small-vessel vasculitis, associated with glomerulonephritis, pulmonary capillaritis, palpable purpura, and antineutrophil cytoplasmic autoantibodies.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
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