microscopic polyangiitis

(redirected from microscopic polyarteritis)

microscopic polyangiitis

systemic, nongranulomatous small-vessel vasculitis, associated with glomerulonephritis, pulmonary capillaritis, palpable purpura, and antineutrophil cytoplasmic autoantibodies.

microscopic polyangiitis

A systemic small-vessel vasculitis that primarily affects the kidneys, skin, and lungs of middle-aged men.

Clinical findings
Fever, malaise, myalgia, weight loss, and autoimmunity, including antineutrophil cytoplasmic antibodies (p-ANCA). Skin lesions occur in 30 to 50%, usually presenting as purpura due to leukocytoclastic vasculitis, less commonly as nodules involving the vessels of the dermis and subcutaneous fat and ulcers. The kidney shows rapidly progressive focal and segmental glomerulonephritis.

DiffDx
Polyarteritis nodosa.

microscopic polyangiitis

Hypersensitivity angiitis, microscopic periarteritis, microscopic polyarteritis Internal medicine The term recommended for necrotizing vasculitis with few or no immune deposits, affecting small vessels–ie, arterioles, capillaries, venules; MP is often accompanied by ANCA, necrotizing glomerulonephritis and pulmonary capillaritis. See Small vessel vasculitis, Systemic vasculitis.

mi·cro·scop·ic pol·y·an·gi·i·tis

(mī'krŏ-skop'ik pol'ē-an'jē-ī'tis)
Systemic, nongranulomatous small-vessel vasculitis, associated with glomerulonephritis, pulmonary capillaritis, palpable purpura, and antineutrophil cytoplasmic autoantibodies.
References in periodicals archive ?
DAH is associated with primary vasculitis (due to conditions such as microscopic polyarteritis, Wegener's granulomatosis, and Churg-Strauss syndrome) and secondary vasculitis accompanying connective tissue diseases (such as SLE and malignant rheumatoid arthritis) [7].
Microscopic polyarteritis: presentation, pathology and prognosis.
(6.) S J HAWORTH, C 0 S SAVAGE, D CARR, J M B HUGHES, A J REES Pulmonary haemorrhage complicating Wegener's granulomatosis and microscopic polyarteritis British Medical Journal.
Renal vasculitis: microscopic polyarteritis and Wegener's granuloma.

Full browser ?