microscopic polyangiitis


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Related to microscopic polyangiitis: polyarteritis nodosa

microscopic polyangiitis

systemic, nongranulomatous small-vessel vasculitis, associated with glomerulonephritis, pulmonary capillaritis, palpable purpura, and antineutrophil cytoplasmic autoantibodies.

microscopic polyangiitis

A systemic small-vessel vasculitis that primarily affects the kidneys, skin, and lungs of middle-aged men.

Clinical findings
Fever, malaise, myalgia, weight loss, and autoimmunity, including antineutrophil cytoplasmic antibodies (p-ANCA). Skin lesions occur in 30 to 50%, usually presenting as purpura due to leukocytoclastic vasculitis, less commonly as nodules involving the vessels of the dermis and subcutaneous fat and ulcers. The kidney shows rapidly progressive focal and segmental glomerulonephritis.

DiffDx
Polyarteritis nodosa.

microscopic polyangiitis

Hypersensitivity angiitis, microscopic periarteritis, microscopic polyarteritis Internal medicine The term recommended for necrotizing vasculitis with few or no immune deposits, affecting small vessels–ie, arterioles, capillaries, venules; MP is often accompanied by ANCA, necrotizing glomerulonephritis and pulmonary capillaritis. See Small vessel vasculitis, Systemic vasculitis.

mi·cro·scop·ic pol·y·an·gi·i·tis

(mī'krŏ-skop'ik pol'ē-an'jē-ī'tis)
Systemic, nongranulomatous small-vessel vasculitis, associated with glomerulonephritis, pulmonary capillaritis, palpable purpura, and antineutrophil cytoplasmic autoantibodies.
References in periodicals archive ?
Deaths occurring during the first year after treatment onset for polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome: A retrospective analysis of causes and factors predictive of mortality based on 595 patients.
Microscopic polyangiitis is a necrotizing vasculitis, with few or no immune deposits, predominantly affecting small vessels, i.
PAN is a potentially remitting disease with a lower relapse rate than granulomatosis with polyangiitis and microscopic polyangiitis.
ANCA-related vasculitides are examined under three main titles including granulomatous polyangiitis (GPA), eosinophilic granulomatous polyangiitis (EGPA) and microscopic polyangiitis (MPA).
Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden.
Prognostic markers in patients with antineutrophil cytoplasmic autoantibodyassociated microscopic polyangiitis and glomerulonephritis.
The majority of patients with PICGN have kidney disease as a part of a systemic small vessel vasculitis including Wegeners granulomatosis and microscopic polyangiitis or as a part of renal limited vasculitis (no other organ involved except kidneys)5.
It is important to note that a negative test does not exclude WG, and positive results can be seen in other vasculitides, including microscopic polyangiitis and allergic granulomatous angiitis.
According to The Chapel Hill Consensus Conference from 1993, in ANCA vasculitis were included Wegener granulomatosus, microscopic polyangiitis and Churg-Strauss syndrome [3].

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