microscopic colitis


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Related to microscopic colitis: collagenous colitis

microscopic colitis

A term of art referring to two distinct conditions clinically characterised by chronic watery diarrhoea and normal colonoscopy and separated based on histopathologic differences: a submucosal band of collagen (collagenous colitis) or a dense lymphoplasmacytic infiltrate in the mucosa (lymphocytic colitis).

microscopic colitis

Abbreviation: MC
Either of two forms of colitis (collagenous and lymphocytic), in which people have chronic, watery diarrhea despite having normal-appearing bowels during endoscopy or radiologic study.
See also: colitis

microscopic colitis

A collective term for collagenous colitis and lymphocytic colitis. Once considered rare gastrointestinal disorders, these conditions are now known to be relatively common and should be considered in the differential diagnosis of persistent watery diarrhoea without blood. Most cases resolve spontaneously but treatment with budesonide and bismuth subsalicylate may be necessary.
References in periodicals archive ?
Casalots et al., "Subepithelial myofibroblasts and tenascin expression in microscopic colitis," Histopathology, vol.
Hultgren Hornquist, "Microscopic colitis patients have increased proportions of [Ki67.sup.+] proliferating and [CD45RO.sup.+] active/memory [CD8.sup.+] and [CD4.sup.+][8.sup.+] mucosal T cells," Journal of Crohn's and Colitis, vol.
Hornquist, "Microscopic colitis patients demonstrate a mixed Th17/Tc17 and Th1/Tc1 mucosal cytokine profile," Molecular Immunology, vol.
Lansoprazole-associated microscopic colitis: a case series.
Randall and his colleagues selected 62 patients with microscopic colitis. About half had self-referred and the rest had been referred for treatment of chronic diarrhea to the gastroenterology clinic at the University of Texas, San Antonio, where Dr.
Microscopic colitis was confirmed by colonoscopy and biopsy.
The end points of the study were complete resolution of diarrhea and histologic resolution of the microscopic colitis. Preliminary findings were presented at DDW 2000; the current findings are a continuation of the open-label study that assessed outcomes after a mean of 22 months.
Microscopic colitis: a common and an easily overlooked cause of chronic diarrhoea.
Atypical forms of microscopic colitis: morphological features and review of the literature.
Microscopic colitis with giant cells: clinico- pathological review of 11 cases and comparison with microscopic colitis without giant cells.
Human leucocyte antigen and TNFalpha polymorphism association in microscopic colitis. Eur J Gastroenterol Hepatol.
Microscopic colitis with granulomatous inflammation.

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