agglutination

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agglutination

 [ah-gloo″tĭ-na´shun]
1. the action of an agglutinant substance.
2. the clumping together in suspension of antigen-bearing cells, microorganisms, or particles in the presence of specific antibodies (agglutinins).
Agglutination reactions. From Applegate, 2000.
3. the process of union of the surfaces of a wound. adj., adj agglutina´tive.
cross agglutination the agglutination of particulate antigen by an antibody raised against a different but related antigen; see also group agglutination.
group agglutination agglutination, usually to a lower titer, of various members of a group of biologically related organisms by an agglutinin specific for one of that group. For instance, the specific agglutinin of typhoid bacilli may agglutinate other members of the colon-typhoid group, such as Escherichia coli and Salmonella enteritidis.
intravascular agglutination clumping of particulate elements within the blood vessels; used conventionally to denote red blood cell agglutination.
platelet agglutination the clumping together of platelets owing to the action of platelet agglutinins; such agglutinins are important in platelet typing.
agglutination test any test based on an agglutination reaction, as serologic tests for specific antibodies.

ag·glu·ti·na·tion

(ă-glū-ti-nā'shŭn),
1. The process by which suspended bacteria, cells, or other particles are caused to adhere and form into clumps; similar to precipitation, but the particles are larger and are in suspension rather than being in solution. For specific agglutination reactions in the various blood groups, see Blood Groups Appendix.
2. Adhesion of the surfaces of a wound.
3. The process of adhering.
[L. ad, to, + gluten, glue]

agglutination

(ə-glo͞ot′n-ā′shən)
n.
1. The act or process of agglutinating; adhesion of distinct parts.
2. A clumped mass of material formed by agglutination. Also called agglutinate.
3. Physiology The clumping together of red blood cells or bacteria, usually in response to a particular antibody.
4. Linguistics The formation of words from morphemes that retain their original forms and meanings with little change during the combination process.

ag·glu′ti·na′tive (-n-ā′tĭv, -ə-tĭv) adj.

agglutination

Lab medicine The clumping of aggregates of antigens or antigenic material-eg bacteria, viruses, with antibodies in a solution. See Latex agglutination test Reproductive biology The conjoining of 2 organisms of the same species for sexual reproduction, which may be mediated by a carbohydrate on one organism and a protein on the other, thereby forming a glycoprotein.

ag·glu·ti·na·tion

(ă-glū'ti-nā'shŭn)
1. The process by which suspended bacteria, cells, or other particles are caused to adhere and form clumps; similar to precipitation, but the particles are larger and are in suspension rather than being in solution.
2. Adhesion of the surfaces of a wound.
3. The process of adhering.
[L. ad, to, + gluten, glue]

agglutination

The clumping and sticking together of normally free cells or bacteria or other small particles so as to form visible aggregates. Agglutination is one of the ways in which ANTIBODIES operate. From the Latin ad , to and glutinare , to glue.

agglutination

a clumping together of cells, usually as a result of reaction between specific ANTIGENS and ANTIBODIES in blood and lymph, forming a natural defence against foreign materials, including bacterial cells. Transfusion of blood between persons of different ABO BLOOD GROUPS is also subject to the risk of agglutination (see UNIVERSAL DONOR and UNIVERSAL RECIPIENT). Agglutination is a different process from BLOOD CLOTTING.

ag·glu·ti·na·tion

(ă-glū'ti-nā'shŭn)
1. The process by which suspended bacteria, cells, or other particles are caused to adhere and form into clumps.
2. Adhesion of the surfaces of a wound.
3. The process of adhering.
[L. ad, to, + gluten, glue]
References in periodicals archive ?
Serology demonstrated positive IgM for leptospira and for Microscopic agglutination test & the infecting serovar was Leptospira hardjo.
A Dot enzyme-linked immunosorbent assay which used a proteinase-K resistant antigen (PK-Dot-ELISA) to detect antileptospiral IgM antibodies was compared to the microscopic agglutination test (MAT).
Samples with positive latex agglutination assay results should be confirmed by microscopic agglutination test (MAT).
Laboratory-confirmed diagnosis of leptospirosis was defined as a 4-fold rise in titer between paired samples or a single titer of [greater than or equal to] 800 in the microscopic agglutination test (MAT) (11) or a positive result on the immunoglobulin M (IgM) ELISA (Bio-Manguinhos, Rio de Janeiro, Brazil) (13).
Serovar * Sex ([dagger]) Pyrogenes M 100 M - F 100 M - M - M - M - F - M - M - F - F - F - F - F - F 100 F 100 M - NK - F 100 F - M 100 F - F - M 100 * Microscopic agglutination test panel included Leptospira interrogans serovars Australis, Autumnalis, Bataviae, Bratislava, Copenhageni, Hardjo, Icterohaemorrhagiae, Pomona, and Pyrogenes; Leptospira borgpetersenii serovar Tarassovi; and Leptospira kirschneri serovar Grippotyphosa.
The microscopic agglutination test was performed with a panel of 24 antigens belonging to 17 serogroups of Leptospira spp.
Microscopic agglutination test (MAT) was performed at the World Health Organization (WHO)/United Nations Food and Agriculture Organization (FAO)/World Animal Health Organisation (OIE) Collaborating Center for Reference and Research on Leptospirosis, Brisbane, Queensland, Australia (4).
Leptospirosis was diagnosed by polymerase chain reaction (PCR) targeted to the flagellin gene (flaB) and confirmed serologically with convalescent-phase serum by microscopic agglutination test. The patient was seronegative and PCR-negative for hantavirus, which causes symptoms similar to those observed in the patient.