micropapillary carcinoma

micropapillary carcinoma

A generic term for a carcinoma characterised by small, tight clusters of neoplastic cells devoid of fibrovascular cores floating in clear spaces, resembling lymphatics or small papillary clusters, and surrounded by prominent stromal desmoplasia. They are often present at high stages with nodal involvement.

Examples
Breast, lung, ovary, salivary duct, thyroid, urothelium.
References in periodicals archive ?
(1) Morphologically, micropapillary carcinoma is defined as small nests and aggregates of tumor cells within lacunae that resemble lymphovascular invasion (Figure 7).
However, they have studied advanced papillary thyroid carcinomas whereas we have studied micropapillary carcinoma patients.
Invasive ductal carcinoma was the most common histology (74.4%); 3.1% of the patients had invasive lobular carcinoma, 11.6% had mixed lobular and ductal histology and 10.9% of the patients had other histologic types including micropapillary carcinoma and apocrine carcinoma.
Pathological tests revealed a 0.4-cm micropapillary carcinoma without a thyroid capsule involvement.
Postoperative pathology showed that micropapillary carcinomas scattered around a major thyroid carcinoma (22 x 11 x 20 mm) in thyroid isthmus, and scattered micropapillary carcinoma also existed on both thyroid right lobe and left lobe (Figures 3-5).
Moreover, 2(0.3%) cases of each of the following were reported: metaplastic carcinoma, apocrine-type carcinoma, and micropapillary carcinoma. Besides, 1(0.1%) case was reported as secretory carcinoma and another one was diagnosed as encapsulated papillary carcinoma.
These rare breast lesions are fibromatosis, idiopathic granulomatous mastitis, tubular adenoma, diabetic mastopathy, invasive micropapillary carcinoma, osteoclastic giant cell breast carcinoma, malignant phyllodes tumor, carcinoma arising in fibroadenoma, metastasis, and metaplastic carcinoma.
Occult micropapillary carcinoma associated with benign follicular thyroid disease and unrelated thyroid neoplasms.
Approximately 96.4% (53 of 55) of the tumors analysed were infiltrative ductal carcinoma, 1.8% (1 of 55) were infiltrative lobular carcinoma, and 1.8% (1 of 55) were micropapillary carcinoma.
According to the World Health Organization (WHO), the definition "thyroid micropapillary carcinoma (TMPC)" is used if the tumor size is less than one centimeter in diameter.
Invasive micropapillary carcinoma of the mammary glands in a mare.
(6,7) The lipoid cell population typically composes 10 50% of the tumour, with the remainder being conventional urothelial carcinoma or another rare subtype, including plasmacytoid and micropapillary carcinoma. (7,8)