micronuclei


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micronuclei

Molecular biology
A term of art for chromosome fragments which are not incorporated into the nucleus at the time of cell division.

Zoology
The smaller nucleus in ciliate protozoans (e.g., Paramecium).

micronucleus

(mī-krō-nū′klē-ŭs) plural.micronuclei [″ + L. nucleus, kernel]
1. A small nucleus.
2. The smaller of the two nuclei of ciliated protozoa; it contains the chromosomes.
References in periodicals archive ?
The mean count of micronuclei in peripheral blood lymphocytes was 3.06 +- 0.639 for group I rats while the mean count of micronuclei in peripheral blood lymphocytes for group II rats was 6.77 +- 0.731.
In the present study, it is hypothesized that using the combined form of seleno-L-methionine and curcumin before exposure to radiation may ameliorate the detrimental effects of ionizing radiation and subsequent micronuclei formation in bone marrow cells.
Ranking in the right down quadrant, the 200 mg/L samples positively correlated with multiple parameters for peroxidation, membrane degradation, mitotic disorders, and micronuclei.
Table 3 shows the frequency of micronuclei (MN) in polychromatic erythrocytes (MNPCEs) and normochromatic erythrocytes (MNNCEs) in all treatment groups.
Elevated frequencies of micronuclei and other nuclear abnormalities in buccal epithelial cells of spray painters in South India.
Although studies evaluating the genotoxicity of exposure to volatile anaesthetics have shown increased formation of chromosomal aberrations, micronuclei and sister chromatid exchanges (SCEs), in vitro and clinical studies evaluating the genotoxicity and mutagenicity of sevoflurane show conflicting results (2-7).
In our study, we aimed to investigate the micronuclei frequency both in peripheral lymphocytes and cervical squamous cells of patients with PCOS in order to demonstrate genetic damage, also in cervical smears.
Keywords: Buccal cell assay, Fuel station attendants, Gasoline, Genotoxicity, Micronuclei, Cytotoxicity.
Micronuclei (MN) test is one of the most used assays in different models to determine chromosomal damage caused by the presence of compounds and mixture of substances (Misik, et al., 2011; Garcia et al., 2011; Hoshina, Angelis, & Marin-Morales, 2008).