nests of tumor cells mold together with one another in a pattern that is often compared to pieces of a jigsaw puzzle or a giraffe's spots.
Clinically, it can be classified into superficial, nodular, pigmented, ulcerating, cystic, and sclerosing patterns. Histological variants are nodular, micronodular
, fibroepithelial, adenoid, morphea form, and infiltrative types. An exceptional appearance as a polypoid lesion is very rare.
Common causes of micronodular
cirrhosis include chronic alcohol usage, hemochromatosis, biliary tract obstruction, chronic venous flow obstruction, and childhood metabolic diseases, and one of the rare causes is cirrhosis secondary to chronic active hepatitis.
On the other hand, micronodular
, morpheaphorm, sclerosing, infiltrative, and basosquamous subtypes are considered to be high-risk due to their tendency for recurrence (6, 7, 8).
As far as histology exam was concerned, macroscopic examination described a nodular tumor of 3.5/3/1.7 cm; seriate sections show a compact, brown-yellow micronodular
Moreover, there were some other radiologic findings such as ground glass opacity in 25 cases (21.4%), micronodular
pattern in 19 cases (16.2%), and emphysema in 16 cases (13.7%) [Figure 1].
Curative-intent treatment can be envisaged with low-volume micronodular
lung or small nodal disease although bone metastases are often resistant to treatment (3).
Churg-Strauss syndrome manifested by appendicitis, cholecystitis and superficial micronodular
liver lesions--an unusual clinicopathological presentation.
Among the latter group, 17 had unilateral adenomas and 4 had bilateral micronodular
or macronodular hyperplasia.
BCCs can be classified into several different types based on their morphologies as follows: nodular BCC, cystic BCC, infundibulocystic BCC, morpheaform/cicatricial BCC, infiltrative BCC, micronodular
BCC, superficial BCC, pigmented BCC, rodent's ulcer, fibroepithelioma of Pinkus, polypoid BCC, pore-like BCC, aberrant BCC, and solitary BCC.
Progressive fibrosis and even micronodular
cirrhosis are evident at later stages.
Stratakis, "Carney complex and other conditions associated with micronodular
adrenal hyperplasias," Best Practice & Research Clinical Endocrinology & Metabolism, vol.