Eukaryotic plasmids with toxoplasma gondii dense granule antigen (GRA 5) and microneme
3 (MIC3) genes as a cocktail DNA vaccine and evaluation of immune responses in BALB/C mice.
Barois et al., "Dual role of the Toxoplasma gondii clathrin adaptor AP1 in the sorting of rhoptry and microneme
proteins and in parasite division," PLoS Pathogens, vol.
Zhou et al., "Toxoplasma gondii microneme
protein 6 (MIC6) is a potential vaccine candidate againsttoxoplasmosisinmice," Vaccine,vol.
(14.) Zhang, L., Maa, L., Liua, R., Zhanga, Y.., Zhanga, S., Hua, C., Songa, M., Caib, J., Wanga, M., Eimeria tenella heat shock protein 70 enhances protection of recombinant microneme
protein MIC2 subunit antigen vaccination against E.
Klinman et al., "In ovo administration of CpG oligodeoxynucleotides and the recombinant microneme
protein MIC2 protects against Eimeria infections," Vaccine, vol.
Full-length AMA1 is an 83-kDa polypeptide that is translocated to the apical organelle microneme
at the time of invasion [13, 14], when the 83-kDa polypeptide undergoes N-terminal processing to form a 66-kDa form that is translocated to the merozoite surface 1,15].
Some sporozoites that are deficient in cell migration, such as spect (sporozoite microneme
protein essential for cell traversal)-/- or spect2-/- sporozoites, are immobilized in the dermis, associated with CD11b+ cells, and destroyed by phagocytes .
proteins in apicomplexans," Sub-Cellular Biochemistry, vol.
The protein, identified by researchers from Boston College as DOC2.1, plays a similar role in the secretion of microneme
organelles that are crucial to the mobility of the parasitic protozoa Toxoplasma gondii, which causes toxoplasmosis, and Plasmodium falciparum, which causes malaria.
N-terminal-tagged GST-VP1s from BKV, JCV, and simian virus 40 (SV40) were generously provided by Michael Pawlita (16), and GST-tagged microneme
(Mic) protein encoded by Toxoplasma gondii was provided by David Sibley.
A conserved subtilisin-like protein TgSUB1 in microneme
organelles of Toxoplasma gondii.
tenella and known to encode a microneme
adhesion involved in parasite motility and host cell invasion by the parasite (Lillehoj et al.