microinvasion

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microinvasion

 [mi″kro-in-va´zhun]
microscopic extension of malignant cells into adjacent tissue in carcinoma in situ. adj., adj microinva´sive.

mi·cro·in·va·sion

(mī'krō-in-vā'zhŭn),
Invasion of tissue immediately adjacent to a carcinoma in situ, the earliest stage of malignant neoplastic invasion.

microinvasion

A generic term for an epithelial malignancy in which the basement membrane has been minimally violated. As a rule, microinvasive cancers measure 1 mm or less in greatest dimension and are designated as Tmic, prognostically between T0 (carcinoma in situ) and T1a in the TNM system. It is also defined as > 1 focus of cancer measuring 2 mm or less in diameter.

mi·cro·in·va·sion

(mī'krō-in-vā'zhŭn)
Invasion of tissue immediately adjacent to a carcinoma in situ, the earliest stage of malignant neoplastic invasion.
References in periodicals archive ?
"These findings allow surgeons to select which patients with microinvasive tumors may actually benefit from lymph node sampling while sparing other patients from this procedure," said Tamera Lillemoe, a study co-author.
That adult T + E exposures alone had limited invasion (17%) and no glandular carcinoma in the lateral prostate, whereas the addition of neonatal BPA produced a 62% incidence of microinvasive carcinoma and 14% glandular carcinoma incidence clearly confirms, for the first time, that early-life BPA exposures heighten prostate cancer risk.
Colposcopic findings: 28 (11.4%) cases were CIN I, 50 (20.4%) cases were CIN II, 150 (61.2%) cases were CIN III, 13 (5.3%) cases were microinvasive carcinoma and four (1.6%) cases were CIS.
In 2004, an 80-year-old Caucasian male underwent bilateral cordectomy for Tis carcinoma in the left cord and microinvasive T1 carcinoma at the right one.
Superficial-type PSCC (STPSCC) is pathologically defined as carcinoma in situ or microinvasive squamous cell carcinoma without invading to the surrounding muscle layer [5].
Microinvasive and invasive carcinomas showed a much higher vimentin expression in 53.0% and 67.0% cases, respectively, findings concordant with our study.
The normal mucosa adjacent to bronchial lesions, intraepithelial lesions, and squamous carcinomas of the lung express MMP3 transcripts [90], while a primarily MMP3 expression is observed in microinvasive and invasive bronchial lesions.
Considering the SA context, our findings suggest that 'first-time' screening at 30 years could be too late for those who may already have invasive or microinvasive cancer.
Nodal disease is often an indication of microinvasive or invasive foci present within the tumour and is rare in pure DCIS tumours, where it may signify the presence of occult microinvasion.