microgranuloma

microgranuloma

(1) A term of art referring to an aggregate of  less than 25 epithelioid histiocytes, usually seen between germinal centres in lymphoid tissue with toxoplasmosis.
(2) A small collection of epithelioid histiocytes which, while nonspecific alone, in the appropriate setting is regarded as characteristic of HIV encephalitis if found in the brain of a patient with AIDS, Crohn’s disease or non-alcoholic fatty liver disease.
References in periodicals archive ?
Additional findings included extensive, acute renal hemorrhage and a single microgranuloma adjacent to a parabronchus in the lung.
A, Loosely formed microgranulomas with associated eosinophils in the liver biopsy specimen of a patient receiving propylthiouracil.
Los microgranulomas se formaron especificamente en respuesta a la infeccion con M.
The presence of lepra bacilli and microgranulomas composed of foamy macrophages, plasma cells and lymphocytes interfering with the normal functioning of the bone marrow could be responsible for the pancytopenia, which resolved within 2 weeks of initiation of anti-leprosy treatment.
Occasional Langerhans cell microgranulomas were seen.
From these exposures, C3H/HeJ and MJ mice, but not BALB/c or C57BL/6 mice, developed T-cell alveolitis, and a subset of these mice developed spontaneously resolving pulmonary microgranulomas.
Immunohistochemical staining for CD68 highlighted numerous macrophages, with a dominance of CD4 lymphocytes in proximity to the microgranulomas.
However, a useful clue to an infectious etiology for PEH is the presence of intraepithelial neutrophilic microabscesses, particularly if they are admixed with microgranulomas.